Evidence map›Paper›PMID 40402810›Full record

ArticleKidney3602025

Indoxyl Sulfate Contributes to Selenium Deficiency and Renal Ferroptosis by Decreasing the Expression of Selenium Transport Protein Selenoprotein P.

Takehiro Nakano, Yutaka Kitazato, Takumu Ogawa, Kai Tokumaru, Yuhi Shintani, Takuma Yoshitake, Kohei Yasuno, Hitoshi Maeda, Motoko Tanaka, Kazutaka Matsushita and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney360, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takehiro NakanoDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Yutaka KitazatoDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0009-0007-0830-4921
Takumu OgawaDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Kai TokumaruDepartment of Clinical Pharmacy and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0002-5086-1031
Yuhi ShintaniDepartment of Clinical Pharmacy and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Takuma YoshitakeDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Kohei YasunoDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Hitoshi MaedaDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0002-0794-9468
Motoko TanakaDepartment of Nephrology, Akebono Clinic, Kumamoto, Japan.
Kazutaka MatsushitaDepartment of Nephrology, Akebono Clinic, Kumamoto, Japan.
Toru MaruyamaDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Hiroshi WatanabeDepartment of Clinical Pharmacy and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.

Funding

Japan Society for the Promotion of Science JST SPRING JPMJSP2127Japan Society for the Promotion of Science KAKENHI JP20H03406Japan Society for the Promotion of Science KAKENHI JP 23K28431
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CKDmineral metabolismuremia

Identifiers

PMID40402810
PMCPMC12483056

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.