SynthesisJournal of medical Internet research2025
Evaluation of the Aspects of Digital Interventions That Successfully Support Weight Loss: Systematic Review With Component Network Meta-Analysis.
Synthesis in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors Influencing the Uptake of Digital Health Interventions for Cardiovascular Disease Prevention Among Healthcare Providers: A Systematic Review.Global heart · 2026Pooled it
- Mobilizing community-led health promotion: Evidence-informed co-development of the Live Well PEI community mobilization platform and integrated granting program.Canadian journal of public health = Revue canadienne de sante publique · 2026Article
- Article
- Integrating Precision Medicine and Digital Health in Personalized Weight Management: The Central Role of Nutrition.Nutrients · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is a chronic complex disease associated with increased risks of developing several serious and potentially life-threatening conditions. It is a growing global health issue. Pharmacological treatment is an option for patients living with overweight or obesity. Digital technology may be leveraged to support patients with weight loss in the community, but it is unclear which of the multiple digital options are important for success.
objectiveThis systematic review and component network meta-analysis aimed to identify components of digital support for weight loss interventions that are most likely to be effective in supporting patients to achieve weight loss goals.
methodsWe searched MEDLINE, Embase, APA PsycInfo, and Cochrane Central Register of Controlled Trials from inception to November 2023 for randomized controlled trials using any weight loss intervention with digital components and assessing weight loss outcomes in adults with BMI ≥25 kg/m
resultsSearches identified 6528 reports, of which 119 were included. After prioritization, 151 trial arms from 68 trials were included in the synthesis. Nine common digital components were identified from the 151 trial arms: provision of information or education, goal setting, provision of feedback, peer support, reminders, challenges or competitions, contact with a specialist, self-monitoring, and incentives or rewards. Of these, 3 components were identified as "best bets" because they were consistently and numerically, but not usually significantly, most likely to be associated with weight loss at 6 and 12 months. These were patient information, contact with a specialist, and incentives or rewards. An exploratory model combining these 3 components was significantly associated with successful weight loss at 6 months (-2.52 kg, 95% CI -4.15 to -0.88) and 12 months (-2.11 kg, 95% CI -4.25 to 0.01). No trial arms used this specific combination of components.
conclusionsOur findings indicate that the design of digital interventions to support weight loss should be carefully crafted around core components. On their own, no single digital component could be considered essential for success, but a combination of information, specialist contact, and incentives warrants further examination.
trial registrationPROSPERO CRD42023493254; https://tinyurl.com/ysyj8j8s.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.