ArticleScientific reports2025
Innovative vibriosis control in open aquaculture: Paratapes undulata as a sustainable growth and resistance enhancer in red tilapia.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cross-Species Dissemination of Pandrug-ResistantMicroorganisms · 2026Article
- SEOH, a novel marine-derived spirostenoid: potent broad-spectrum antimicrobial activity against multidrug-resistant aquaculture pathogens.Applied microbiology and biotechnology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study demonstrates the novel therapeutic potential of Paratapes undulata for mitigating Vibrio alginolyticus infection in red tilapia. In vivo, P. undulata significantly improved growth by approximately 362% in group G3 (Clam-treated Control) and 284% in group G4 (Clam-treated Infected), compared to the infected control group (G2), and reduced mortality by 100% in group G3 and 75% in group G4, compared to the infected control group (G2), and alleviated clinical signs, correlating with enhanced hematological and biochemical profiles, and reduced tissue damage. Mechanistically, P. undulata modulated the immune response by shifting cytokine balance towards anti-inflammation, enhanced antioxidant capacity, and directly inhibited Vibrio alginolyticus virulence. Gas Chromatography-Mass Spectrometry and Fourier-Transform Infrared Spectroscopy analyses revealed the presence of bioactive compounds contributing to these effects. These findings establish P. undulata as a promising, natural, and sustainable biocontrol agent for vibriosis in aquaculture, offering a novel strategy for disease management and reducing reliance on antibiotics. This study suggests that P. undulata can be effectively incorporated into aquaculture feed or water treatments to prevent and manage vibriosis outbreaks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.