Evidence map›Paper›PMID 40405519›Full record

ArticlePhysiological reports2025

An exaggerated blood pressure response to exercise is associated with attenuated exercise-induced acute cognitive improvement: A pilot study.

Narumi Kunimatsu, Hayato Tsukamoto, Takuro Washio, Shotaro Saito, Marino Karaki, Hervé Normand, Shigehiko Ogoh

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Narumi KunimatsuDepartment of Biomedical Engineering, Toyo University, Asaka, Japan.
Hayato TsukamotoFaculty of Sport Sciences, Waseda University, Tokorozawa, Japan.ORCID https://orcid.org/0000-0001-5512-0497
Takuro WashioInstitute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas, Dallas, Texas, USA.
Shotaro SaitoDepartment of Biomedical Engineering, Toyo University, Asaka, Japan.ORCID https://orcid.org/0000-0003-1133-0091
Marino KarakiSchool of Health and Sport Sciences, Chukyo University, Toyota, Japan.
Hervé NormandUniversité de CAEN Normandie, Caen, France.
Shigehiko OgohDepartment of Biomedical Engineering, Toyo University, Asaka, Japan.ORCID https://orcid.org/0000-0001-5297-6468

Funding

This work was supported by JSPS KAKENHI JP23K24727
6 · The paper itself

Abstract

Some individuals, despite having normal resting blood pressure, exhibit an exaggerated blood pressure response during exercise, indicating a potential risk for future hypertension. This study aimed to investigate how different individual blood pressure responses to exercise affect cerebral circulation and exercise-induced acute cognitive changes in young, healthy individuals. To eliminate the influence of aging and disease, thirty young, healthy individuals (aged 21 ± 1 years) participated in this study. They performed an interval static handgrip exercise protocol, during which arterial blood pressure (ABP), cognitive function, and middle cerebral artery blood velocity (MCA V), as an index of cerebral blood flow, were measured. Cognitive function was assessed using the Go/No-go test before exercise and 3 min after exercise completion. Individual changes in systolic blood pressure (SBP) were significantly and linearly related to the decrease in reaction time during a cognitive task, indicating cognitive improvement following exercise (p < 0.01). Importantly, in the top 10 subjects with the highest SBP responses (n = 10, + 38 ± 8 mm Hg), this cognitive improvement was not statistically significant (p = 0.32). These findings suggest that an exaggerated ABP response to exercise may compromise acute cognitive enhancements induced by exercise in young individuals.

Indexed as

Blood PressureCognitionExerciseAdultBlood Flow VelocityCerebrovascular CirculationFemaleHand StrengthHumansMaleMiddle Cerebral ArteryPilot ProjectsYoung Adultblood pressurecerebral blood flowcognitive functionstatic exercise

Identifiers

PMID40405519
PMCPMC12098951

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.