Evidence map›Paper›PMID 40407098›Full record

ArticleGut microbes2025

Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages.

Adrián Cortés-Martín, Colin Buttimer, Jessie L Maier, Ciara A Tobin, Lorraine A Draper, R Paul Ross, Manuel Kleiner, Colin Hill, Andrey N Shkoporov

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Phase variation inEngineering microbiology · 2026
    Article
  5. Article
  6. We need to talk about the virome.Microbiome research reports · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. The Microbiome and Metabolic Dysfunction-Associated Steatotic Liver Disease.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Adrián Cortés-MartínAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.ORCID 0000-0001-5542-4984
Colin ButtimerAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.ORCID 0000-0002-3361-8902
Jessie L MaierDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.
Ciara A TobinAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.
Lorraine A DraperAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.
R Paul RossAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.ORCID 0000-0003-4876-8839
Manuel KleinerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.ORCID 0000-0001-6904-0287
Colin HillAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.ORCID 0000-0002-8527-1445
Andrey N ShkoporovAPC Microbiome Ireland & School of Microbiology, University College Cork, Cork, Ireland.ORCID 0000-0002-5547-8672

Funding

DNA transduction in intestinal microbiomes and the spread of pathogenicity traitsR01AI171046 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Breck A Duerkop, Manuel Kleiner · 2024 to 2026
$2.2M
Metaproteomics to investigate intestinal microbiota-host and -diet interactionsR35GM138362 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KLEINER, MANUEL · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI171046NIGMS NIH HHS R35 GM138362Wellcome TrustWellcome Trust 220646/Z/20/Z
6 · The paper itself

Abstract

Bacteriophages (phages) and bacteria within the gut microbiome persist in long-term stable coexistence. These interactions are driven by eco-evolutionary dynamics, where bacteria employ a variety of mechanisms to evade phage infection, while phages rely on counterstrategies to overcome these defenses. Among the most abundant phages in the gut are the crAss-like phages that infect members of the order Bacteroidales, in particular, genus

Indexed as

BacteriophagesBacteroidesBacteroidetesGastrointestinal MicrobiomeAdaptation, PhysiologicalHumansProteomicsBacteriophagesBacteroidesco-culturecrassphagesCrassviralesgut microbiomeintestinal microbiotaParabacteroidesphage-bacteria interactionvirome

Identifiers

PMID40407098
PMCPMC12118408

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.