Evidence map›Paper›PMID 40407135›Full record

ArticleZoological research2025

Features and mechanisms of long-lived

Xiao-Yan Huang, Xiu-Yun Liu, Wei Wang, Gao-Jing Liu, You-Long Zhu, Xiao Wen, Kai-Qin Li, Bo Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao-Yan HuangKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
Xiu-Yun LiuKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
Wei WangKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
Gao-Jing LiuKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
You-Long ZhuDepartment of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650033, China.
Xiao WenKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
Kai-Qin LiKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
Bo ZhaoKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The DNA replication stress (RS) response is crucial for maintaining cellular homeostasis and promoting physiological longevity. However, the mechanisms by which long-lived species, such as bats, regulate RS to maintain genomic stability remain unclear. Also, recent studies have uncovered noncanonical roles of ribosome-associated factors in maintaining genomic stability. In this study, somatic skin fibroblasts from the long-lived big-footed bat (

Indexed as

ChiropteraDNA ReplicationFibroblastsStress, PhysiologicalAnimalsGene Expression RegulationLongevityMiceDNA replication stressLong-lived speciesMyotis pilosusNufip1P53 signalingRibosome biogenesisRps27l

Identifiers

PMID40407135
PMCPMC12361907

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.