Evidence map›Paper›PMID 40407856›Full record

SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

The use of DBS in the treatment of childhood cerebral palsy: a systematic review.

Marcelo Anchieta Rohde, Rhaná Carolina Santos, Rafaela Jucá Lindner, Cristiano Mendes Ribeiro, Caroline Saldanha Custódio, Fernando Vélez Feijó, Amauri Dalla Corte

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcelo Anchieta RohdeSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil. marcelo.rohde@hotmail.com.
Rhaná Carolina SantosSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil.
Rafaela Jucá LindnerSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil.
Cristiano Mendes RibeiroSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil.
Caroline Saldanha CustódioSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil.
Fernando Vélez FeijóSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil.
Amauri Dalla CorteSchool of Medicine, University of Vale Do Rio Dos Sinos (UNISINOS), São Leopoldo (RS), Brazil.ORCID http://orcid.org/0000-0002-0402-5550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy and safety of DBS as a therapeutic intervention for managing motor symptoms and improving quality of life in patients with CP.

methodsA systematic review was conducted following PRISMA guidelines. Studies were selected from PubMed, SCIELO, and the Regional Portal of BVS using defined inclusion criteria, assessing DBS outcomes on motor function, quality of life, and adverse events. The GRADE system evaluated the risk of bias.

resultsOf the 11 studies reviewed, 107 patients aged 5 to 26 years were included. Most studies focused on bilateral GPi stimulation, with nine reporting improvements in motor symptoms. However, outcomes varied, with significant benefits observed primarily in younger patients. Complications occurred in 22.4% of patients, predominantly infections and device-related issues.

conclusionThis review showed that GPi DBS can improve motor symptoms and reduce disability in patients with CP, although outcomes are variable and influenced by patient characteristics, such as age. Further large-scale longitudinal studies are necessary to optimize candidate selection and enhance long-term outcomes.

Indexed as

Cerebral PalsyDeep Brain StimulationAdolescentChildChild, PreschoolHumansQuality of LifeTreatment OutcomeYoung AdultCerebral palsyDeep brain stimulationDystoniaMotor dysfunctionSystematic review

Identifiers

PMID40407856

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.