Evidence map›Paper›PMID 40408559›Full record

ArticleOcular immunology and inflammation2025

Visual Function and Intraocular Pressure Outcomes Following Surgical Intervention in Pediatric Patients with Inflammatory Glaucoma.

Abhiram R Manda, Xiangyu Ji, Jordan Comstock, Stephen J Kim, Qingxia Chen, Karen Joos, Sapna S Gangaputra

Abstract read
In one paragraph

Article in Ocular immunology and inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abhiram R MandaSchool of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Xiangyu JiVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jordan ComstockVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Stephen J KimVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Qingxia ChenVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Karen JoosVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Sapna S GangaputraVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Ocular Inflammatory Mediators in the Pathophysiology of Diabetic RetinopathyR01EY031315 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIM, STEPHEN JAE · 2020 to 2024
$2.1M
Ocular Therapeutic Delivery Through Real-time Endoscopic B-scan OCT-guided Tools and Robotic AssistanceR01EY028133 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JOOS, KAREN MARGARET, SIMAAN, NABIL · 2018 to 2022
$2.0M
Intraoperative Optical Coherence Tomography for Ophthalmic Surgical GuidanceR01EY030490 · NEI · VANDERBILT UNIVERSITY · PI TAO, YUANKAI KENNY · 2019 to 2023
$1.8M
Intraoperative imaging of macular hole repair to predict visual function outcomesR01EY031769 · NEI · VANDERBILT UNIVERSITY · PI TAO, YUANKAI KENNY · 2020 to 2023
$1.4M
Outcomes of uveitic cataract and uveitic glaucoma surgeryR21EY032592 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GANGAPUTRA, SAPNA S · 2021 to 2022
$488k
NEI NIH HHS P30 EY008126NEI NIH HHS R01 EY028133NEI NIH HHS R01 EY030490NEI NIH HHS R01 EY031315NEI NIH HHS R01 EY031769NEI NIH HHS R21 EY032592
6 · The paper itself

Abstract

purposeThis study evaluates the outcomes of pediatric uveitic glaucoma eyes that received surgery compared to non-surgical pediatric uveitis eyes.

methodsA retrospective chart review was performed of patients diagnosed with inflammatory glaucoma before the age of 18 years. Outcomes, including intraocular pressure (IOP), visual acuity (VA), and inflammatory activity were assessed over two years.

resultsThirty-six eyes (18 surgically managed, 18 non-surgical) were included in this study. At baseline the surgical eyes had significantly higher median IOP than the non-surgical pediatric uveitis eyes (31.5 mmHg versus 15.0 mmHg;

conclusionOur data showcases that glaucoma surgery in patients with well controlled uveitis, can provide significant benefit to patients that are refractory to medical management, by reducing IOP and glaucoma medication burden, with excellent visual outcomes at two years.

Indexed as

GlaucomaIntraocular PressureTrabeculectomyUveitisVisual AcuityAdolescentChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesTonometry, OcularTreatment OutcomeGlaucoma surgerypediatric ophthalmologypractice managementuveitic glaucomauveitis

Identifiers

PMID40408559
PMCPMC12224628

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.