Evidence map›Paper›PMID 40409378›Full record

ReviewThe Journal of allergy and clinical immunology2025

Frequent exacerbator-a novel endotype of pediatric asthma.

Kieran J Phelan, Gurjit K Khurana Hershey

Abstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kieran J PhelanDivision of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Gurjit K Khurana HersheyDivision of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: gurjit.hershey@cchmc.org.

Funding

TSLP, IL-9-producing mucosal mast cells, and allergic inflammationU19AI070235 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Marc E. Rothenberg · 2006 to 2026
$31.3M
Medical Scientist Training ProgramT32GM063483 · NIGMS · UNIVERSITY OF CINCINNATI · PI KHURANA HERSHEY, GURJIT K. · 2002 to 2022
$6.7M
Pulmonary Development and Disease Pathogenesis Training ProgramT32HL007752 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Francis Xavier McCormack, Anne-Karina Theresia Perl · 1994 to 2026
$6.3M
Multi-omics of the Frequent Exacerbator AsthmaticU01AI159087 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Gurjit K. Khurana Hershey · 2021 to 2026
$3.0M
Pathogenesis of frequent asthma exacerbatorsF30HL172613 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Kieran Phelan · 2024 to 2026
$152k
NHLBI NIH HHS F30 HL172613NHLBI NIH HHS T32 HL007752NIAID NIH HHS U01 AI159087NIAID NIH HHS U19 AI070235NIGMS NIH HHS T32 GM063483
6 · The paper itself

Abstract

Asthma is a complex and chronic respiratory condition that affects both adult and pediatric populations. Several asthma endotypes have been described; they include endotypes characterized by T

Indexed as

AsthmaTh2 CellsChildDisease ProgressionHumansPhenotypeAsthmaendotypesexacerbationfrequent exacerbators

Identifiers

PMID40409378
PMCPMC12229750

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.