Evidence map›Paper›PMID 40410155›Full record

Trial reportNutrition & diabetes2025

Investigating the effects of mycoprotein and guar gum on postprandial glucose in type 2 diabetes: a double-blind randomised controlled trial.

Anna Cherta-Murillo, Kexin Zhou, Martina Tashkova, James Frampton, Ana Cláudia Cepas de Oliveira, Claire Ho, Georgia Franco-Becker, Edward S Chambers, Anne Dornhorst, Gary S Frost

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition & diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna Cherta-MurilloSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.ORCID 0000-0002-2482-9898
Kexin ZhouSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
Martina TashkovaSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
James FramptonSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
Ana Cláudia Cepas de OliveiraSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
Claire HoSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
Georgia Franco-BeckerSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
Edward S ChambersSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK.
Anne DornhorstImperial College Healthcare NHS Trust, Hammersmith Hospital, London, W12 0NN, UK.
Gary S FrostSection for Nutrition Research, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, W12 0NN, UK. g.frost@imperial.ac.uk.ORCID 0000-0003-0529-6325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes (T2D) is highly prevalent, particularly among south Asian populations, and diet is the first-line strategy to manage postprandial glucose (PG) response. Mycoprotein and guar gum reduce PG in normo-glycaemic people. This study investigates the independent and interactive effects of mycoprotein and guar gum on PG, insulin and appetite responses in white Europeans and south Asians with T2D.

methodsIn this double-blind, crossover, acute, randomised controlled trial, 18 subjects with T2D (10 white European, 8 south Asian) completed six separate visits consuming soy, chicken, and mycoprotein with and without guar gum. Incremental area under the curve (iAUC

resultsWe found independent effects of mycoprotein, guar gum and ethnicity on PG iAUC

conclusionMycoprotein and guar gum promote significant independent effects in lowering PG in both white European and south Asians with T2D.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2GalactansMannansPlant GumsPostprandial PeriodAdultAgedAnimalsAppetiteAsian PeopleChickensCross-Over StudiesDouble-Blind MethodFemaleGlucagon-Like Peptide 1Blood GlucoseGalactansGlucagon-Like Peptide 1guar gumInsulinMannansPlant Gums

Identifiers

PMID40410155
PMCPMC12102162

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.