Evidence map›Paper›PMID 40410733›Full record

ArticleBMC public health2025

Phenotypes of successful living among adolescents with HIV in Rwanda: a latent profile analysis.

Dieudonne Kayiranga, Darius Gishoma, Gallican Rwibasira, Eric Remera, Donatilla Mukamana, Michael V Relf, Wei Pan

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dieudonne KayirangaSchool of Nursing and Midwifery, University of Rwanda, Remera Campus, 11 KG 47, Kigali, Rwanda. kayiranga2@yahoo.co.uk.
Darius GishomaDivision of Mental Health, Rwanda Biomedical Center, Kigali, Rwanda.
Gallican RwibasiraDivision of HIV/AIDS and STIs Diseases, Rwanda Biomedical Center, Kigali, Rwanda.
Eric RemeraDivision of Research Innovation and Data Science, Rwanda Biomedical Center, Kigali, Rwanda.
Donatilla MukamanaSchool of Nursing and Midwifery, University of Rwanda, Remera Campus, 11 KG 47, Kigali, Rwanda.
Michael V RelfDuke University School of Nursing, Durham, NC, USA.
Wei PanDuke University School of Nursing, Durham, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV remains a major public health concern globally, and 85% of adolescents with HIV (AWH) live in Sub-Saharan Africa (SSA). Despite advances in treatment and prevention efforts, adolescents continue to be disproportionately affected by HIV and are a group with poor adherence to antiretroviral medication. We identified phenotypes of successful living among adolescents with HIV in Rwanda.

methodsA multi-stage stratified random sampling was used to collect data from 300 AWH using a validated and piloted questionnaire from four provinces and Kigali City in Rwanda. Data were collected in August 2023 and were analyzed using latent profile analysis (LPA). The following variables were computed to measure their associations and determine the latent profiles (or phenotypes) of successful living: viral load, number of sex partners in a lifetime, condom use during sex, adherence to HIV antiretroviral therapy, HIV stigma, depressive symptoms, state of hope, self-esteem, resilience, disclosure, HIV quality of life, and perceived social support.

resultsThe two distinct profiles of successful living among adolescents with HIV were identified through LPA: 46% of adolescents struggled to live with HIV (the first profile) while 54% of adolescents lived successfully with HIV (the second profile). There are several factors associated with successful living among AWH. Successful living was positively associated with spirituality, residing with family members, a stable home environment, psychological well-being, social support, and acquiring HIV through vertical transmission. The adherence to ART, HIV-related stigma, levels of depression, hope, self-esteem, resilience, availability of social support, and patterns of disclosure of HIV status are determinants of adolescents' experiences of living with HIV. Additionally, adolescents tend to struggle to live with HIV in late adolescence, especially when the factors associated with successful living are not met.

conclusionsThis study identified two profiles of Successful Living among AWH. Our results suggest developing profile-oriented, tailored interventions to improve the quality of life and health outcomes of AWH.

Indexed as

HIV InfectionsQuality of LifeAdolescentFemaleHumansMalePhenotypeResilience, PsychologicalRwandaSelf ConceptSocial StigmaSocial SupportSurveys and QuestionnairesViral LoadAdolescentHIVLatent profile analysisPhenotypesSuccessful living

Identifiers

PMID40410733
PMCPMC12100999

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.