Evidence map›Paper›PMID 40411172›Full record

ArticleNMR in biomedicine2025

Hybrid Multidelay PCASL Acquired With Time-Encoded and Variable-TR Schemes for the Assessment of Cerebral Perfusion in Moyamoya Disease.

Osamu Togao, Makoto Obara, Koji Yamashita, Kazufumi Kikuchi, Tatsuhiro Wada, Chiaki Tokunaga, Ryoji Mikayama, Koichi Arimura, Ataru Nishimura, Shota Ishida and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Osamu TogaoDepartment of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-5910-7852
Makoto ObaraPhilips Japan, Tokyo, Japan.
Koji YamashitaDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kazufumi KikuchiDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tatsuhiro WadaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Chiaki TokunagaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Ryoji MikayamaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Koichi ArimuraDepartment of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Ataru NishimuraDepartment of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Shota IshidaDepartment of Radiological Technology, Faculty of Medical Sciences, Kyoto College of Medical Science, Kyoto, Japan.
Lena VáclavůC.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Matthias J P van OschC.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.ORCID https://orcid.org/0000-0001-7034-8959
Kim van de VenPhilips Healthcare, Best, the Netherlands.
Marc van CauterenPhilips Japan, Tokyo, Japan.
Kousei IshigamiDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Funding

JSPS KAKENHI JP 23K07137
6 · The paper itself

Abstract

Multidelay arterial spin labeling (ASL) MRI requires balancing temporal information with signal-to-noise ratio (SNR). A hybrid scheme combines the high SNR of time-encoded pseudo-continuous ASL (PCASL) with the temporal flexibility of variable-TR PCASL. The purpose of the present study was to assess the SNR and quantitative performance of the hybrid scheme by comparing it to time-encoded and variable-TR schemes for evaluating cerebral perfusion in patients with moyamoya disease. Twenty patients with moyamoya disease (8 men and 12 women, 27.6 ± 22.7 years) were scanned with 3 T MRI system. Variable-TR PCASL with 12 delays (vTR12), time-encoded PCASL with seven delays (TEnc7), and hybrid PCASL with 12 (4 × 3) delays (Hyb12) were obtained. Hyb12 and vTR12 were configured with nearly identical label duration (LD) and postlabeling delay (PLD) settings. For TEnc7, it was balanced so that the maximum LD + PLD time is the same. Time-corrected SNR (SNR

Indexed as

Cerebrovascular CirculationMagnetic Resonance ImagingMoyamoya DiseaseAdolescentAdultFemaleHumansMaleMiddle AgedSignal-To-Noise RatioSpin LabelsTime FactorsYoung AdultSpin Labelsarterial spin labelingcerebral perfusionMoyamoya disease

Identifiers

PMID40411172
PMCPMC12102644

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.