Evidence map›Paper›PMID 40411980›Full record

ArticleDifferentiation; research in biological diversity

New genetic tools to define the pathophysiology of inborn errors of cobalamin metabolism impacting mammalian development.

Tiffany Chern, Xuefei Tong, William G Bauer, David J Quispe-Parra, Xia Gao, Kamryn N Gerner-Mauro, Ross A Poché

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Differentiation; research in biological diversity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tiffany ChernDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA; Graduate Program in Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA.
Xuefei TongDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
William G BauerDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA; Genetics and Genomics Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA.
David J Quispe-ParraDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA; Genetics and Genomics Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA.
Xia GaoChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Ave., Houston, TX, 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Kamryn N Gerner-MauroDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
Ross A PochéDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA; Graduate Program in Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA; Development, Disease Models and Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA; Genetics and Genomics Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA; Cancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA. Electronic address: poche@bcm.edu.

Funding

Ronin (Thap11) in Neural Crest Cell DevelopmentR01DE028298 · NIDCR · BAYLOR COLLEGE OF MEDICINE · PI POCHE, ROSS ANTHONY · 2019 to 2023
$2.6M
Transcriptional regulation of retinal mitochondrial function and cell cycleR01EY024906 · NEI · BAYLOR COLLEGE OF MEDICINE · PI POCHE, ROSS ANTHONY · 2015 to 2019
$2.3M
THE ROLE OF VITAMIN B12-DEPENDENT METABOLIC PATHWAYS IN NEURAL CREST DEVELOPMENTR01HD116761 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Ross Anthony Poche · 2025 to 2026
$1.1M
NEI NIH HHS R01 EY024906NICHD NIH HHS R01 HD116761NIDCR NIH HHS R01 DE028298
6 · The paper itself

Abstract

The congenital, autosomal recessive disorder combined methylmalonic acidemia and homocystinuria - cblC type, is the most common inborn error of cobalamin (vitamin B

Indexed as

Amino Acid Metabolism, Inborn ErrorsHomocystinuriaMetabolism, Inborn ErrorsVitamin B 12Vitamin B 12 DeficiencyAnimalsDisease Models, AnimalHumansMiceMutationVitamin B 12

Identifiers

PMID40411980
PMCPMC13520071

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.