Evidence map›Paper›PMID 40413311›Full record

ArticleScientific reports2025

Fat mass in postmenopausal women with osteoporosis is associated with cognitive function.

Dongxue Zhang, Zijing Zhu, Lu Xue, Yifeng Zheng, Xiongfeng Li, Miyang Xu, Xinfang Xie, Yongli Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Preventive Regulation of Bone Marrow Mesenchymal Stem Cell Differentiation by α-Zearalenol Ameliorates Bone Loss in Osteoporotic Rats].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dongxue Zhang *Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China.
Zijing Zhu *Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China.
Lu XueHuzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China.
Yifeng ZhengHuzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China.
Xiongfeng LiHuzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China.
Miyang XuHuzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, China.
Xinfang Xie *Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China. xxf7281517@163.com.
Yongli Wang *Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China. wyl1944@hzhospital.com.

Funding

General Medical and Health Projects in Zhejiang Province 2024KY414General Public Welfare Application Research Project of Huzhou Science and Technology Bureau (Class B) 2023GYB65
6 · The paper itself

Abstract

Postmenopausal women undergo significant changes in endogenous hormones, which lead to reduced bone mineral density (BMD) and alterations in body composition. However, the relationship between body composition and cognitive function in this demographic has not yet been explored. This study aims to examine this relationship in postmenopausal women with osteoporosis.This survey will involve 120 postmenopausal women with osteoporosis. Dual-energy X-ray absorptiometry (DXA) will be used to assess L1-L4 BMD, fat mass (FM), trunk fat mass (TFM), fat-free mass (FFM), and appendicular skeletal muscle mass (ASMM). The relationship between body composition and cognitive function will be analyzed using t-tests and multiple linear regression.Our findings suggest that in postmenopausal women with osteoporosis, cognitive function (MMSE score) is positively correlated with body composition indicators such as FM and BMD, and positively correlated with educational level, but negatively correlated with age. FM plays a significant role in influencing cognitive function and is a crucial indicator of body composition in postmenopausal women with osteoporosis.

Indexed as

Adipose TissueCognitionOsteoporosis, PostmenopausalPostmenopauseAbsorptiometry, PhotonAgedBody CompositionBone DensityFemaleHumansMiddle AgedBody compositioncognition functionfat-free massfat masspostmenopausal osteoporosis

Identifiers

PMID40413311
PMCPMC12103549

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.