Evidence mapPaperPMID 40413680Full record

ReviewDiscover oncology2025

Golden insights for exploring cancer: delivery, from genes to the human body using bimetallic Au/Ag nanostructures.

Misbah Ullah Khan, Humaira Aslam, Jehanzeb Sohail, Ali Umar, Aman Ullah, Hayat Ullah

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Misbah Ullah KhanCentre for Nanosciences, University of Okara, Okara, 56130, Pakistan. Misbahullahkhan143@uo.edu.pk.
Humaira AslamCentre for Nanosciences, University of Okara, Okara, 56130, Pakistan.
Jehanzeb SohailCentre for Nanosciences, University of Okara, Okara, 56130, Pakistan.
Ali UmarDepartment of Zoology, Faculty of Life Sciences, University of Okara, Okara, 56130, Pakistan.
Aman UllahDepartment of Zoology, Faculty of Life Sciences, University of Okara, Okara, 56130, Pakistan.
Hayat UllahDepartment of Chemistry, University of Okara, Okara, 56130, Pakistan. hayatullah@uo.edu.pk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sweeping contact with cancer continues to rise globally, which has led to advanced research on new treatment approaches; nanotechnology has become crucial to targeted cancer therapy. Within the intimate of nanomaterials, Au/Ag nanostructures have emerged as highly attractive because of their distinctive desirable characteristics and their prospective roles in diagnosis as well as cancer therapy. The nanostructures developed revealed remarkable biocompatibility, optically recursive alteration, and magnificently improved therapeutic effects of gold and silver in conjunction with each other. This review addresses the molecular and systemic aspects of Au/Ag nanostructures in cancer research, including the impact of nanostructures on the molecular genetic pathways and their use of systemic administration in the human organism. We explain some of the related mechanisms of action, such as photothermal therapy (PTT), and photodynamic therapy (PDT), as well as the drug delivery systems where they display potential benefits towards offering a more targeted treatment approach with fewer side effects. The latest development has shown that they have the prospect of real-time imaging and biomarker identification, and owing to this they are being viewed as a tool for individualized treatment. However, there are still some limitations: challenges of scaling up, biological safety, and bringing it to the clinic. It is therefore incumbent upon these managements to overcome these hurdles to optimize for their impact. As a result, the current findings are briefly reviewed, and the development directions are discussed to support the revolutionary role of Au/Ag nanostructures in cancer research and therapy.

Indexed as

DetectionGold nanoparticlesGold/silver nanostructuresNanotechnologyPDTPersonalized medicinePTTTherapyTumor

Identifiers

PMID40413680
PMCPMC12104135

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.