Evidence map›Paper›PMID 40413720›Full record

ArticleJournal of veterinary internal medicine

The Vertebrate Breed Ontology: Toward Effective Breed Data Standardization.

Kathleen R Mullen, Imke Tammen, Nicolas A Matentzoglu, Marius Mather, James P Balhoff, Elizabeth Esdaile, Gregoire Leroy, Carissa A Park, Halie M Rando, Nadia T Saklou and 6 more

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Myotonia Congenita in Australian Merino Sheep with a Missense Variant inAnimals : an open access journal from MDPI · 2024
    Article
  3. A Splice Site Variant inAnimals : an open access journal from MDPI · 2024
    Article
  4. Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Kathleen R MullenDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-5002-8648
Imke TammenSydney School of Veterinary Science, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-5520-6597
Nicolas A MatentzogluSemanticly Ltd, Athens, Greece.ORCID https://orcid.org/0000-0002-7356-1779
Marius MatherSydney Informatics Hub, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-3616-6235
James P BalhoffRenaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-8688-6599
Elizabeth EsdaileVeterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, California, USA.ORCID https://orcid.org/0000-0001-6238-9793
Gregoire LeroyAnimal Production and Health Division, Food and Agriculture Organization of the United, Rome, Italy.ORCID https://orcid.org/0000-0003-2588-4431
Carissa A ParkDepartment of Animal Science, Iowa State University, Ames, Iowa, USA.ORCID https://orcid.org/0000-0002-2346-5201
Halie M RandoDepartment of Computer Science, Smith College, Northampton, Massachusetts, USA.ORCID https://orcid.org/0000-0001-7688-1770
Nadia T SaklouDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0001-7894-3947
Tracy L WebbDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0003-4547-3787
Nicole A VasilevskyData Collaboration Center, Critical Path Institute, Tucson, Arizona, USA.ORCID https://orcid.org/0000-0001-5208-3432
Christopher J MungallLawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID https://orcid.org/0000-0002-6601-2165
Melissa A HaendelDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0001-9114-8737
Frank W NicholasSydney School of Veterinary Science, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-9178-3965
Sabrina ToroDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-4142-7153

Funding

Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
Translational Research Workforce Training: Leveraging the Veterinary SpecialistU01TR002953 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI TREPANIER, LAUREN A · 2019 to 2024
$2.6M
The Colorado Building Interdisciplinary Research Careers in Women's Health ProgramK12AR084226 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER, Nanette F. Santoro · 2023 to 2026
$2.5M
National Institute of Food and Agriculture 2022-67015-36217NCATS NIH HHS U01 TR002953NCATS NIH HHS U01TR002953-05NCATS NIH HHS UM1 TR004399NIAMS NIH HHS K12AR084226NIH Office of the Director 5R24OD011883Ronald Bruce Anstee bequest to the Sydney School of Veterinary Science for the Anstee Hub for Inherited Diseases in AnimalsUniversity of North Carolina at Chapel Hill Department of Genetics
6 · The paper itself

Abstract

backgroundLimited universally-adopted data standards in veterinary medicine hinder data interoperability and therefore integration and comparison; this ultimately impedes the application of existing information-based tools to support advancement in diagnostics, treatments, and precision medicine. HYPOTHESIS/

objectivesA single, coherent, logic-based standard for documenting breed names in health, production, and research-related records will improve data use capabilities in veterinary and comparative medicine. ANIMALS: No live animals were used.

methodsThe Vertebrate Breed Ontology (VBO) was created from breed names and related information compiled from the Food and Agriculture Organization of the United Nations, breed registries, communities, and experts, using manual and computational approaches. Each breed is represented by a VBO term that includes breed information and provenance as metadata. VBO terms are classified using description logic to allow computational applications and Artificial Intelligence-readiness.

resultsVBO is an open, community-driven ontology representing over 19 500 livestock and companion animal breed concepts covering 49 species. Breeds are classified based on community and expert conventions (e.g., cattle breed) and supported by relations to the breed's genus and species indicated by National Center for Biotechnology Information (NCBI) Taxonomy terms. Relationships between VBO terms (e.g., relating breeds to their foundation stock) provide additional context to support advanced data analytics. VBO term metadata includes synonyms, breed identifiers/codes, and attributed cross-references to other databases. CONCLUSION AND CLINICAL IMPORTANCE: The adoption of VBO as a standard for breed names in databases and veterinary electronic health records enhances veterinary data interoperability and computability, supporting precision medicine.

Indexed as

Biological OntologiesBreedingLivestockVertebratesVeterinary MedicineAnimalsanimal population groupsbiological ontologiesbreedinggeneticsprecision medicinetheriogenology

Identifiers

PMID40413720
PMCPMC12103836

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.