Evidence map›Paper›PMID 40415215›Full record

ArticleRenal failure2025

Association between the serum uric acid-to-creatinine ratio and cardiovascular mortality in maintenance hemodialysis patients.

Wanqing Huang, Ning Ding, Yanping Zhang, Dongxia Qiu, Lin Wei, Chen Zhao, Zhuo Ren, Qian Wang, Kaiming Ren, Jiuxu Bai and 1 more

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wanqing HuangDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Ning DingDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Yanping ZhangDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Dongxia QiuDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Lin WeiDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Chen ZhaoDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Zhuo RenDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Qian WangDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Kaiming RenDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Jiuxu BaiDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.
Ning CaoDepartment of Blood Purification, General Hospital of Northern Theater Command, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUric acid is a risk factor for death in hemodialysis patients, but its exact role is still unclear. The serum uric acid-to-serum creatinine (SUA/SCr) ratio is a new indicator. This study aimed to clarify the relationship between this indicator and cardiovascular death in maintenance hemodialysis patients.

methodsKaplan-Meier analysis was used to compare all-cause and cardiovascular mortality. Restricted cubic splines were used to plot the relationships between SUA/SCr and all-cause and cardiovascular mortality. Multivariable Cox regression was used to analyze the relationships between SUA/SCr and the risk of all-cause death or cardiovascular death. The C statistic was calculated to test the model discrimination performance. The net reclassification index was calculated to demonstrate the prediction accuracy of SUA and SUA/SCr.

resultsKaplan-Meier analysis showed that all-cause and cardiovascular mortality were significantly higher in the highest SUA/SCr quartile (

conclusionsIn maintenance hemodialysis patients patients, higher levels of SUA/SCr are associated with a greater risk of cardiovascular mortality.

Indexed as

Cardiovascular DiseasesCreatinineKidney Failure, ChronicRenal DialysisUric AcidAgedBiomarkersCause of DeathFemaleHumansKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsBiomarkersCreatinineUric Acidcardiovascular mortalitycreatinineHemodialysisuric acid

Identifiers

PMID40415215
PMCPMC12107642

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.