ArticleBiomarkers in medicine2025
First-trimester neutrophil percentage-to-albumin ratio: a novel predictor for preeclampsia.
Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- First-Trimester Neutrophil Percentage-to-Albumin Ratio Adds Meaningful Additive Prognostic Utility for Early-Onset Preeclampsia: A Nested Case-Control Study.Journal of clinical medicine · 2026Article
- Assessment of albumin-related inflammatory indices in preeclampsia and their relationship with composite adverse perinatal outcomes.BMC pregnancy and childbirth · 2026Article
- The NFAT5-AR Axis Is Associated with Hyperosmolarity, Renal Dysfunction, and Neutrophil-Related Inflammatory Markers in Diabetic Retinopathy.International journal of molecular sciences · 2026Article
- Threshold-dependent effect of the neutrophil-to-albumin ratio (NAR) in early pregnancy: a novel insight for preeclampsia risk prediction.American journal of translational research · 2026Article
- Prognostic evaluation of albumin-associated inflammatory indices (LAR, NAR, MAR, FAR, SII/Alb, SIRI/Alb, NPAR, and CAR) in preterm premature rupture of membranes (PPROM) pregnancies.BMC pregnancy and childbirth · 2025Article
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3 authors.
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Abstract
objectiveThis retrospective study evaluated the predictive power of a new marker for pre-eclampsia (PE), the neutrophil percentage/albumin ratio (NPAR).
methodsA total of 399 participants consisting of 133 pregnant women diagnosed with PE and 266 healthy pregnant controls were included in the study. Data collected included demographic and obstetric history, gestational age at diagnosis, maternal hematological and biochemical parameters, first trimester neutrophil/albumin ratio (NAR) and NPAR values, and neonatal outcomes.
resultsThe pre-eclampsia group showed significantly higher NAR (mean: 312.30, range: 80.00-1568.00) and NPAR (mean: 3.14 ± 0.81) compared to the control group (mean NAR: 234.40, range: 78.16-725.00; mean NPAR: 2.06 ± 0.38;
conclusionNPAR is elevated in PE compared to healthy pregnancies, demonstrating its potential as a simple yet effective biomarker for predicting PE.
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