Evidence mapPaperPMID 40415473Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2025

A Mixed-Methods Study Exploring the Feasibility of a Digital Combined Lifestyle Intervention for Patients With Post Covid-19 Condition.

Debbie Gach, Charlotte D C Born, Lisanne L T Schuurman, Frits H M van Osch, Joop P van den Bergh, Sanne M P L Gerards, Rik Crutzen, Annemie M W J Schols, Rosanne J H C G Beijers, P4O2 Consortium

Abstract readMulticenter Study
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Debbie GachDepartment of Respiratory Medicine, NUTRIM, Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.ORCID https://orcid.org/0009-0000-3333-7492
Charlotte D C BornDepartment of Respiratory Medicine, NUTRIM, Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Lisanne L T SchuurmanDepartment of Respiratory Medicine, NUTRIM, Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Frits H M van OschDepartment of Clinical Epidemiology, VieCuri Medical Centre, Venlo, the Netherlands.
Joop P van den BerghDepartment of Internal Medicine, VieCuri Medical Centre, Venlo, the Netherlands.
Sanne M P L GerardsDepartment of Health Promotion, NUTRIM, Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Rik CrutzenDepartment of Health Promotion, CAPHRI, Care and Public Health Research Institute, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Annemie M W J ScholsDepartment of Respiratory Medicine, NUTRIM, Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Rosanne J H C G BeijersDepartment of Respiratory Medicine, NUTRIM, Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
P4O2 Consortium

Funding

This study was funded by the Partners in the Precision Medicine for more Oxygen (P4O2) consortium, which includes the Amsterdam UMC, Leiden University Medical Center, Maastricht UMC+, Maastricht University, UMC Groningen, UMC Utrecht, Utrecht University, TNO, Abbvie, Aparito, Boehringer Ingelheim, Breathomix, Clear, Danone Nutricia Research, Fluidda, Ncardia, Olive, Ortec Logiqcare, Philips, Proefdiervrij, Quantib-U, RespiQ, Roche, Smartfish, SODAQ, Thirona, TopMD, Lung Alliance Netherlands (LAN) and the Lung Foundation Netherlands (Longfonds). The consortium is additionally funded by the PPP Allowance made available by Health Holland, Top Sector Life Sciences & Health (LSHM20104 and LSHM20068) to stimulate public-private partnerships and by Novartis.
6 · The paper itself

Abstract

introductionLow physical activity and poor dietary quality can negatively influence Covid-19 recovery and increase the risk and duration of post-Covid-19 condition (PCC). This proof-of-concept nested intervention study aimed to evaluate the feasibility of a digital personalised combined lifestyle intervention (CLI) in patients with PCC using a mixed-methods design, assessing compliance, experiences and perceived effectiveness.

methodsA nested intervention study, incorporating motivational interviewing aiming to enhance physical activity and dietary quality, was conducted within a multicentre prospective cohort study including 95 post-Covid-19 patients (aged 40-60) between May 2021 and September 2022. Patients in the intervention and control groups were followed at ±3-6 and ±12-15 months post Covid-19. The intervention consisted of nine monthly individual counselling sessions (30 min), two interactive-group sessions (60 min), and three educative webinars (45 min). Additionally, a nutritional supplement (NS; Remune, Smartfish, Oslo, Norway) high in omega-3 fatty acids, vitamin D and protein was provided to facilitate recovery. After the intervention, a process evaluation was conducted, comprising an evaluation questionnaire and semi-structured in-depth interviews.

resultsThe intervention-to-treat group consisted of 47 patients (age 54.7 ± 6.0 years; 40% males; BMI 30.6 ± 5.8 kg/m

conclusionA digital personalised CLI was well-received among patients with PCC regarding compliance, experiences and perceived effectiveness. These findings will guide the development and implementation of tailored interventions to enhance overall well-being among patients with PCC. PATIENT OR PUBLIC CONTRIBUTION: Patients' experiences regarding the design and implementation of the study were retrieved. Although participants were not directly involved in the initial design of the study, their experiences were actively incorporated into the refinement and implementation of the study procedures, thereby ensuring meaningful patient involvement.

Indexed as

COVID-19Life StylePost-Acute COVID-19 SyndromeAdultDietDietary SupplementsExerciseFeasibility StudiesFemaleHumansMaleMiddle AgedMotivational InterviewingProspective StudiesSARS-CoV-2dietdietary supplementsdigital healthhealthy lifestylephysical activitypost‐Covid‐19 conditionproof‐of‐concept study

Identifiers

PMID40415473
PMCPMC12104566

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.