ArticleFrontiers in global women's health2025
Global, regional, and national trends and burden of hypertensive disorders in pregnancy among women of childbearing age from 1990 to 2021.
Article in Frontiers in global women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biomarkers of endothelial glycocalyx dysfunction in pregnancy: a systematic review of clinical relevance and detection techniques.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Pooled it
- Age at Menarche and Risk of Hypertensive Disorders of Pregnancy: A Retrospective Cohort Study.Clinics and practice · 2026Article
- Maternal Mortality Among Black Women in Brazil: A Retrospective Cohort Study.International journal of environmental research and public health · 2026Article
- Temporal Trends and Future Projections of Oral Disorders Among Women of Childbearing Age in South Korea.International journal of women's health · 2026Article
- Global, regional and national burden of colorectal cancer attributable to low-fiber diet from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.Frontiers in nutrition · 2026Article
- Global, regional, and national burden and trends of idiopathic epilepsy among children and adolescents from 1990 to 2021: insights from the global burden of disease study 2021.Annals of medicine · 2025Article
- An explainable machine learning model for predicting preterm birth in pregnant women with gestational diabetes mellitus and hypertensive disorders of pregnancy: development and external validation.Frontiers in endocrinology · 2025Article
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4 authors.
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Abstract
Background: Hypertensive disorders of pregnancy (HDP) are a significant cause of maternal and perinatal morbidity and mortality worldwide. This study aims to use the Global Burden of Disease 2021 database to analyze the prevalence trends and disease burden of HDP across the globe from 2019 to 2021. Methods: We analyzed four key metrics related to HDP (prevalence, incidence, mortality, and DALYs) using data from the GBD Database. Trends were assessed using the estimated annual percentage change (EAPC) and changes in disease burden. Results: In 2021, global HDP prevalence cases, incidence cases, mortality cases, and DALYs were 3.51 million, 18.00 million, 37.58 million, and 2.44 million, respectively, with percentage changes of 14%, 15%, -29%, and -29% over the study period. Prevalence and incidence rates increased (EAPCs: -0.7 and -0.67), while mortality and DALYs rates decreased (EAPCs: -2.29 and -2.28). Low Socio-demographic Index (SDI) regions had the highest HDP burden, accounting for about half of the global total. The 25-29 age group had the highest incidence cases. Conclusion: Over the past 32 years, HDP prevalence cases and incidence cases have risen globally, but death cases and DALYs cases have significantly decreased, particularly in low SDI regions and the 25-29 age group. The global HDP burden is higher in regions with lower SDI. Our findings highlight regional and age-related disparities in HDP, providing a basis for targeted interventions and prevention strategies.
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