Evidence map›Paper›PMID 40415983›Full record

ArticleHealth science reports2025

A Retrospective Analysis Assessing Paravalvular Leak and Pacemaker Implantation Using TEE and Non-Contrast CT for CKD Patients Compared With CT Angiography for Annular Sizing Pre-TAVR.

Michael O'Shaughnessy, Roxana Tabrizi, Derek Pham, Nicholas Jackson, Olcay Aksoy, Andre Akhondi, Jeanne Huchting, Richard Shemin, Murray Kwon, Peyman Benharash and 2 more

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michael O'ShaughnessyDepartment of Medicine David Geffen School of Medicine Los Angeles California USA.ORCID https://orcid.org/0000-0003-1402-935X
Roxana TabriziDepartment of Medicine David Geffen School of Medicine Los Angeles California USA.
Derek PhamDepartment of Medicine, Division of General Internal Medicine and Health Services Research David Geffen School of Medicine Los Angeles California USA.
Nicholas JacksonDepartment of Medicine, Division of General Internal Medicine and Health Services Research David Geffen School of Medicine Los Angeles California USA.
Olcay AksoyDepartment of Medicine, Division of Cardiology David Geffen School of Medicine Los Angeles California USA.
Andre AkhondiDepartment of Medicine, Division of Cardiology David Geffen School of Medicine Los Angeles California USA.
Jeanne HuchtingDepartment of Medicine, Division of Cardiology David Geffen School of Medicine Los Angeles California USA.
Richard SheminDepartment of Surgery, Division of Cardiac Surgery David Geffen School of Medicine Los Angeles California USA.
Murray KwonDepartment of Surgery, Division of Cardiac Surgery David Geffen School of Medicine Los Angeles California USA.
Peyman BenharashDepartment of Surgery, Division of Cardiac Surgery David Geffen School of Medicine Los Angeles California USA.
Brandon KimUniversity of California Los Angeles California USA.
Amir RabbaniDepartment of Medicine, Division of Cardiology David Geffen School of Medicine Los Angeles California USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Transcatheter aortic valve replacement (TAVR) has become the treatment of choice for many patients with severe aortic stenosis. Proper pre-procedure sizing of the aortic annulus is crucial in preventing post-TAVR complications. This is typically performed with CT angiography, but the use of contrast is controversial in patients with chronic kidney disease (CKD). Methods: This study of 557 patients from 2016 to 2021 sought to evaluate a contrast-sparing protocol for balloon expandable TAVR evaluation in patients with CKD, in which patients with glomerular filtration rate of less than 40 would undergo transesophageal echocardiogram (TEE) and CT without contrast (83 patients) for aortic annular sizing instead of CT angiography (445 patients). Results: We found that there was no significant difference in rates of greater than trace or greater than mild paravalvular leak between the two groups at hospital discharge, 30 days, or 1-year post-TAVR. We also found no difference in rates of permanent pacemaker implantation at these same time points. Conclusions: This suggests that TEE and non-contrast CT could be a viable alternative to CTA in patients with CKD, although more research into other variables such as mortality and other post-procedural complications is necessary.

Indexed as

aortic stenosispacemaker implantationparavalvular leakTAVRtranscatheter aortic valve replacement

Identifiers

PMID40415983
PMCPMC12098966

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.