Evidence mapPaperPMID 40416236Full record

ArticleCureus2025

Sex-Specific Effects of Cumin Supplementation on Body Composition, Lipid Levels, and Glycemic Profiles: A Pilot Study.

Shin Suzuki, Ayako Otsuka, Etsuko Kurata, Kimito Mio, Tasuku Inaba, Kentaro Yoshida, Shoji Kinoshita, Toyohiro Hamaguchi, Eun Sangsoo, Masahiro Abo

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Shin SuzukiDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, JPN.
Ayako OtsukaDepartment of Nutrition, Koyama Rehabilitation Hospital, Shizuoka, JPN.
Etsuko KurataDepartment of Nutrition, Koyama Rehabilitation Hospital, Shizuoka, JPN.
Kimito MioDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, JPN.
Tasuku InabaDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, JPN.
Kentaro YoshidaDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, JPN.
Shoji KinoshitaDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, JPN.
Toyohiro HamaguchiDepartment of Rehabilitation, Graduate School of Health Sciences, Saitama Prefectural University, Saitama, JPN.
Eun SangsooDepartment of Rehabilitation Medicine, Koyama Rehabilitation Hospital, Shizuoka, JPN.
Masahiro AboDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCumin ( DESIGN AND

methodsWe conducted a before-and-after trial with 29 healthy adults aged 22-74 at a single facility. After a two-month pre-intervention period, participants consumed 2 g of cumin powder daily for two months. We measured body composition using bioelectrical impedance analysis. Additionally, we assessed blood biomarkers, including lipid and blood glucose profiles, at baseline and both before and after the intervention period. We analyzed the data using Student's t-tests and Wilcoxon rank-sum tests.

resultsIn women, cumin intake significantly reduced the extracellular-to-total body water ratio and increased phase angle, suggesting improved muscle quality. Low-density lipoprotein cholesterol (LDL-C) decreased significantly in both sexes, while high-density lipoprotein cholesterol (HDL-C) decreased in men only. There were no significant changes in glucose profiles.

conclusionCumin showed sex-specific effects on body composition and lipid profiles. Muscle quality improved in women only following cumin consumption, and while its effects on LDL-C were similar in both sexes, its effects on HDL-C were specific to men. These findings indicate that cumin's health benefits vary by sex, highlighting its potential for personalized use.

Indexed as

body compositioncuminlipid profilemuscle qualitysex differences

Identifiers

PMID40416236
PMCPMC12098769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.