Evidence map›Paper›PMID 40416362›Full record

ArticleResearch (Washington, D.C.)2025

Gut Microbiota Modulation by Lysozyme as a Key Regulator of Vascular Inflammatory Aging.

Chenyang Zhang, Xin Zhao, Hang Zhang, Tongtong Wang, Zhenyu Zhang, Yilin Yin, Hui Wang, Xiao Tong, Yuzheng Xue, Yahong Zhou and 5 more

Erratum issuedAbstract read
In one paragraph

Article in Research (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Chenyang ZhangInstitute of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Jiangnan University, Wuxi 214122, China.
Xin ZhaoDepartment of Rehabilitation Treatment, Jiangsu Rongjun Hospital, Wuxi 214062, China.
Hang ZhangDepartment of Pathology, Army Medical University, Chongqing 400038, China.
Tongtong WangWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Zhenyu ZhangWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Yilin YinWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Hui WangWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Xiao TongDepartment of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi 214122, China.
Yuzheng XueDepartment of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi 214122, Jiangsu, China.
Yahong ZhouWuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi 214071, Jiangsu, China.
Fenglai YuanInstitute of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Jiangnan University, Wuxi 214122, China.
Xiuwu BianDepartment of Pathology, Army Medical University, Chongqing 400038, China.
Hong WeiYu-Yue Pathology Scientific Research Center, Jinfeng Laboratory, Chongqing 401329, China.
Yuan HuangNational Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China.ORCID https://orcid.org/0000-0002-1420-8932
Tianhao LiuInstitute of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Jiangnan University, Wuxi 214122, China.ORCID https://orcid.org/0000-0002-3997-756X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular inflammatory aging is strongly associated with multimorbidity, including immunosenescence. Here, bioinformatic analysis indicated elevated expression of the lysozyme (LYZ) gene in age-dependent vascular diseases.

Identifiers

PMID40416362
PMCPMC12099208

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.