Evidence map›Paper›PMID 40417782›Full record

Trial reportRespirology (Carlton, Vic.)2025

Inspiratory Muscle Training on Exercise Capacity, Dyspnoea and Health Status in Pulmonary Hypertension: A Randomised Controlled Trial.

Fabrício Farias da Fontoura, Gabriela Roncato, Gisela Martina Bohns Meyer, Cássia da Luz Goulart, Fernanda Brum Spilimbergo, Gerson Cipriano Junior, Marilia Gabriela Bernadeli, Katya Rigatto, Danilo Cortozi Berton

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Respirology (Carlton, Vic.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabrício Farias da FontouraPrograma de Pós-graduação em Ciências Pneumologicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.ORCID 0000-0001-5366-6293
Gabriela RoncatoPrograma de Pós-graduação em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Gisela Martina Bohns MeyerCentro de Hipertensão Pulmonar, Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.
Cássia da Luz GoulartCentro de Hipertensão Pulmonar, Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.
Fernanda Brum SpilimbergoCentro de Hipertensão Pulmonar, Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.
Gerson Cipriano JuniorResearch Group on Cardiopulmonary Rehabilitation (GPRC), University of Brasilia (UnB), Brasilia, Brazil.
Marilia Gabriela BernadeliCentro de Hipertensão Pulmonar, Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.
Katya RigattoPrograma de Pós-graduação em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.ORCID 0000-0001-7773-2902
Danilo Cortozi BertonPrograma de Pós-graduação em Ciências Pneumologicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo evaluate the effects of a high-intensity inspiratory muscle training on respiratory muscle strength, exercise capacity, dyspnoea, and health-related quality of life (HRQL) in patients with pulmonary hypertension (PH).

methodsSingle-blinded, randomised controlled trial 35 women with clinically stable PH (subgroups 1 and 4), functional class II and III, were randomly assigned to a high-intensity inspiratory muscle training (IMT) or sham training. Daily 8-week IMT protocol with 50% (IMT-50%) of maximal inspiratory muscle pressure (PImax) or sham training with a fixed load of 3 cmH

resultsThere were significantly greater improvements in the intervention group (17 patients) compared to sham (14 patients) on PImax [Δpost-pre = 56.4 cmH

conclusionsA high-intensity protocol of IMT improves respiratory muscle strength, exercise capacity, and dyspnoea in symptomatic patients with PH.

trial registrationThe trial was recorded on the Trials registry RBR-33gm3k (https://ensaiosclinicos.gov.br/rg/RBR-33gm3k).

Indexed as

Breathing ExercisesDyspneaExercise ToleranceHealth StatusHypertension, PulmonaryRespiratory MusclesAdultAgedFemaleHumansMiddle AgedMuscle StrengthQuality of LifeSingle-Blind MethodTreatment Outcomeexercise capacityIMTPImaxpulmonary hypertension

Identifiers

PMID40417782
PMCPMC12321694

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.