ReviewMolecular medicine reports2025
Exosomal miRNAs in pancreatitis: Mechanisms and potential applications (Review).
Review in Molecular medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Long non-coding RNA AC245100.4 for early diagnosis and prognostic assessment in acute pancreatitis: clinical value and inflammation-regulatory mechanisms.Frontiers in pharmacology · 2026Article
- Exosomal miRNA signatures in pancreatogenic diabetes: beyond islet destruction toward early diagnosis and precision biomarkers.Annals of medicine and surgery (2012) · 2025Article
- RNA signaling in skeletal muscle: the central role of microRNAs and exosomal microRNAs.Frontiers in cell and developmental biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pancreatitis, an inflammatory disorder of the pancreas, remains a significant clinical challenge owing to its complex pathogenesis and the lack of reliable biomarkers for early diagnosis and effective treatment. Exosomes, small extracellular vesicles containing a variety of biomolecules including microRNAs (miRNAs), have been identified as key mediators of intercellular communication. Emerging evidence highlight the pivotal role of exosomal miRNAs in the regulation of pancreatic inflammation, fibrosis and cellular responses during pancreatitis. The present review comprehensively examined the mechanisms by which exosomal miRNAs contribute to the pathophysiology of pancreatitis. It discussed the effect of exosomal miRNAs on various cell types, such as pancreatic acinar cells, immune cells and pancreatic stellate cells, highlighting their roles in modulating inflammation, fibrosis and tissue remodeling. Furthermore, it explored the potential of exosomal miRNAs as non‑invasive biomarkers for diagnosing pancreatitis and predicting disease progression. The present review provided an overview of current research and discusses future directions for exosomal miRNA‑based therapies, offering new insights into potential strategies for managing pancreatitis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.