Evidence map›Paper›PMID 40418352›Full record

ArticleNatural products and bioprospecting2025

Polyprenylated acylphloroglucinols from Garcinia species and structural revision of seven analogues.

Yong-Ge Fu, Yi-Qi Huang, Zhi-Hong Xu, Xia Liu, Xing-Wei Yang

Abstract read
In one paragraph

Article in Natural products and bioprospecting, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yong-Ge Fu *School of Pharmaceutical Sciences (Shenzhen), Sun Yat-Sen University, Shenzhen, 518107, People's Republic of China.
Yi-Qi Huang *School of Pharmaceutical Sciences (Shenzhen), Sun Yat-Sen University, Shenzhen, 518107, People's Republic of China.
Zhi-Hong XuSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-Sen University, Shenzhen, 518107, People's Republic of China.
Xia LiuDepartment of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400021, China. liuxia1@cdutcm.edu.cn.
Xing-Wei YangSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-Sen University, Shenzhen, 518107, People's Republic of China. yang-xingwei@foxmail.com.ORCID http://orcid.org/0000-0002-9578-2986

Funding

Natural Sciences Foundation of China 82404843Natural Sciences Foundation of Guangdong Province 2025A1515010551State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University CMEMR2023-B11
6 · The paper itself

Abstract

Our continuous study of the fruits of Garcinia xanthochymus and Garcinia subelliptica led to the isolation and structural characterization of six new polyprenylated acylphloroglucinols, xanthochymusones N and O (1 and 2), (-)-garciyunnanin L (3), and garsubelones C-E (4-6), together with two known analogues. Their structures were elucidated by interpretation of NMR and MS spectroscopic data. It was found that the Grossman-Jacobs rule is no longer applicable to determination of the C-7 configuration of compounds 1-3, as they possess a complex 6/6/6/6/6 fused ring system. The inhibitory activities of all the compounds against two human hepatocellular carcinoma cell lines Huh-7 and HepG2 were evaluated, and compound 1 exhibited moderate cytotoxic activities against HepG2 cells with IC

Indexed as

CytotoxicityGarcinia subellipticaGarcinia xanthochymusPolyprenylated acylphloroglucinolStructural revision

Identifiers

PMID40418352
PMCPMC12106175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.