Evidence map›Paper›PMID 40418438›Full record

ReviewInflammopharmacology2025

Integrating natural products with modern medicine in the treatment of gouty arthritis: a review.

Sherif S Abdel Mageed, Fatma Abdelhakim Mohamed, Marina Sobhy, Ahmed H Elosaily, Ahmed M El-Dessouki, Heba R Ghaiad, Mai A Abd-Elmawla, Mohamed I Fahmy, Mennat-Allah M Hassan, Riham A El-Shiekh and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sherif S Abdel MageedPharmacology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, Cairo, 11829, Egypt.
Fatma Abdelhakim MohamedDepartment of Pharmacognosy, Faculty of Pharmacy, Heliopolis University, Cairo, 11785, Egypt.
Marina SobhyDepartment of Pharmacognosy, Faculty of Pharmacy, Heliopolis University, Cairo, 11785, Egypt.
Ahmed H ElosailyDepartment of Pharmacognosy, Faculty of Pharmacy, Ahram Canadian University, Giza, 12573, Egypt.
Ahmed M El-DessoukiPharmacology and Toxicology Department, Faculty of Pharmacy, Ahram Canadian University, 6th of October City, Giza, 12566, Egypt.
Heba R GhaiadBiochemistry Department, Faculty of Pharmacy, Cairo University, Kasr el Ainy St,, Cairo, 11562, Egypt.
Mai A Abd-ElmawlaBiochemistry Department, Faculty of Pharmacy, Cairo University, Kasr el Ainy St,, Cairo, 11562, Egypt.
Mohamed I FahmyDepartment of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), P.O. Box 77, Giza, Egypt.
Mennat-Allah M HassanDepartment of Pharmacology & Toxicology Department, Faculty of Pharmacy, Heliopolis University, Cairo, Egypt.
Riham A El-ShiekhDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. riham.adel@pharma.cu.edu.eg.ORCID http://orcid.org/0000-0002-3179-3352
Nourhan M AbdelmaksoudDepartment of Biochemistry, Faculty of Pharmacy, Heliopolis University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gout is an inflammatory form of arthritis caused by hyperuricemia, a condition in which uric acid levels in the body become excessively high. When this occurs, monosodium urate (MSU) crystals can accumulate in the joints, triggering intense pain, swelling, and inflammation. If left untreated, gout can lead to joint damage and other complications. Diet is a key factor in the development and management of gout since some meals may increase uric acid levels while others can help relieve symptoms. To reduce circulating urate levels, commonly used drugs include allopurinol and febuxostat. However, the intake of these medications is associated with undesirable side effects. As a result, the development of a novel active, safe anti-hyperuricaemic and anti-inflammatory medicine could be extremely beneficial in gout treatment. Natural products have become a source of new medications because of their high efficacy and low side effects, which are based on the presence of complex bioactive components. A rising number of researchers document that traditional medications can reduce serum urate levels. This article is intended to trace which herbal remedies could alleviate hyperuricemia, as well as their mechanism of actions.

Indexed as

ArthritisGoutHerbal medicinesHyperuricemiaInflammationSerum urate

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.