Evidence map›Paper›PMID 40418878›Full record

ReviewPharmacological reviews2025

5-HT

Benjamin R Cummins, Gerald B Billac, David E Nichols, Charles D Nichols

Abstract readReview
In one paragraph

Review in Pharmacological reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Deconstruction of lysergic acid diethylamide.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Integrated 5-HTMolecular psychiatry · 2026
    Article
  11. Review
  12. Dissociating the Hallucinogenic and Neuroplastic Effects of Psilocybin.bioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Ibogalogs Activate the 5-HTNeurochemical research · 2026
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin R CumminsDepartment of Pharmacology and Experimental Therapeutics, LSU Health Sciences Center, New Orleans, Louisiana.
Gerald B Billac2A Biosciences, New Orleans, Louisiana.
David E Nichols2A Biosciences, Chapel Hill, North Carolina.
Charles D NicholsDepartment of Pharmacology and Experimental Therapeutics, LSU Health Sciences Center, New Orleans, Louisiana. Electronic address: cnich1@lsuhsc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotonin 5-HT

Indexed as

Receptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor AgonistsAnimalsHallucinogensHumansMental DisordersSerotonin 5-HT2 Receptor AntagonistsHallucinogensReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor AgonistsSerotonin 5-HT2 Receptor Antagonists

Identifiers

PMID40418878
PMCPMC12405928

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.