ArticleScientific reports2025
Cyperus rotundus mediated green synthesis of silver nanoparticles for antibacterial wound dressing applications.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Plant-Mediated Silver Nanoparticle Formulations for Wound Healing: A Process-Property-Performance Perspective.Pharmaceutics · 2026Review
- Biosynthesis of Silver Nanoparticles UsingMolecules (Basel, Switzerland) · 2026Article
- Are Silver and Gold Nanoparticles Obtained by 'Green' Synthesis Biocompatible?Nanomaterials (Basel, Switzerland) · 2026Review
- CarbopolGels (Basel, Switzerland) · 2026Article
- Matrix-Dependent Stability and Antibacterial Efficacy of Silver Nanoparticles: A Comparative Study of Anionic Carbopol vs. Non-Ionic Pluronic Hydrogels.Pharmaceutics · 2026Article
- Silver Nanoparticles in Antibacterial Research: Mechanisms, Applications, and Emerging Perspectives.International journal of molecular sciences · 2026Review
- Green-Synthesized Metal Nanoparticles Coated With Chitosan: Enhanced Stability and Antimicrobial Potential Against ESKAPE Pathogens.Chemistry & biodiversity · 2026Article
- Biopolymer Hydrogel-Based Nanocomposites Functionalized with Natural Products for Wound Dressings: Translational Advances in Drug Design, Development, and Therapeutic Wound Care.Drug design, development and therapy · 2026Review
- Naringin and Naringenin Functionalized Silver Nanoparticles: Synthesis, Characterization and Biological Evaluation.Pharmaceutics · 2025Article
- Smart hybrid nanomaterials for chronic infections: microbiome-responsive and sustainable therapeutic platforms.Journal of nanobiotechnology · 2025Review
- Recent Advances of Silver Nanoparticles in Wound Healing: Evaluation of In Vivo and In Vitro Studies.International journal of molecular sciences · 2025Review
- Nanomaterial-based encapsulation of biochemicals for targeted sepsis therapy.Materials today. Bio · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing is a complex biological process that can be hindered by persistent infections and inflammation, especially in the presence of multidrug-resistant (MDR) bacteria. Silver nanoparticles (AgNPs) have demonstrated significant antimicrobial efficacy; however, concerns regarding their toxicity have limited their therapeutic application.
methodsIn this study, we developed a biocompatible Ag-NPs-based hydrogel using Cyperus rotundus extract via a green synthesis approach for prospective wound healing applications. The synthesized AgNPs were characterized for their physicochemical properties, confirming their stability and antibacterial potency against E. coli and S. epidermidis. The Ag-NPs-loaded hydrogel was formulated using Carbopol 974P and evaluated for its physicochemical properties, antibacterial activity, anti-inflammatory potential, and cytotoxicity.
resultsCharacterization studies confirmed the successful synthesis of AgNPs, exhibiting potent antibacterial, antioxidant, and anti-inflammatory properties. The Ag-NPs-loaded hydrogel demonstrated significant wound contraction in an excision wound model, comparable to standard treatment. Additionally, in vitro safety evaluations confirmed excellent biocompatibility, minimizing toxicity concerns associated with conventional silver formulations.
conclusionsThese findings suggest that the developed Ag-NPs-based hydrogel is an effective, natural, and safer alternative for advanced wound care, warranting further clinical validation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.