ReviewNutrition & metabolism2025
The effects of the mediterranean diet supplemented with olive oils on pro-inflammatory biomarkers and soluble adhesion molecules: a systematic review and meta-analysis of randomized controlled trials.
Review in Nutrition & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Glucose Metabolism in Immune Regulation: From Mechanisms to Therapeutic Opportunities.Journal of cellular biochemistry · 2026Review
- Nutrient-Sensitive Epigenetic Modifiers as Candidate Biomarkers of Metabolic Dysfunction in Obesity: A Nutrigenomic Review.International journal of molecular sciences · 2026Review
- In Vitro Effects of Minor Olive Oil Compounds on Prostacyclin/Thromboxane Balance Under Acute High-Glucose Conditions.Biomolecules · 2026Article
- Biological Cardiovascular Age Derived from Coronary CTA Reports Using a Large Language Model: A Novel Predictor of Major Adverse Cardiovascular Events?Diagnostics (Basel, Switzerland) · 2026Article
- Metabolic Inflammation as a Common Thread in Cardio-Endocrine Diseases: Toward a Unified Therapeutic Framework.Cureus · 2026Review
- Article
- Mediterranean Diet, Inflammation, and Neurovulnerability: Towards Personalized Nutritional Strategies.Nutrients · 2025Article
- Unveiling the anti-inflammatory potential of olive leaf phenolic extracts in diabetes-related endothelial dysfunction.Frontiers in endocrinology · 2025Article
- Olive tree at the intersection of environment, public health, and One Health: a sustainable path to global wellbeing.Frontiers in public health · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation plays a pivotal role in Cardiovascular disease (CVD) which are a major global health burden. The oil-supplemented Mediterranean diet (MED) is associated with anti-inflammatory effects. The current study evaluates the impact of an olive oils-supplemented MED on pro-inflammatory biomarkers and soluble adhesion molecules.
methodsRegarding PRISMA guideline, this study was conducted and PubMed, Scopus, Web of Science (ISI), Embase, CINAHL databases as well as Google Scholar and Cochrane Library were systematically searched till June 2024.
results15 clinical trials (20 arms) comprising 2477 adults aged 23-80 years were included in the systematic review and 9 of them were entered in the meta-analysis. We revealed that following an enriched MED with olive oils can reduce Interleukin-6 (IL-6) (SMD: - 1.85; 95% CI: -3.69 to -0.01, I
conclusionsThe olive oils-supplemented MED demonstrates significant anti-inflammatory benefits and improvements in soluble adhesion molecules, supporting its role in reducing CVD risk. However, further studies are required to address the high heterogeneity and confirm these findings in diverse populations. TRIAL REGISTRATION/PROTOCOL REGISTRATION: PROSPERO (CRD42023425225).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.