ArticleBMC nutrition2025
Association of lipid composition with diabetic foot ulcer size and depth: a cross-sectional study on plant versus animal oils, cholesterol, and omega fatty acids.
Article in BMC nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association of high-density lipoprotein-related inflammatory indicators with diabetic foot ulcer in patients with diabetes: a population-based study.Diabetology & metabolic syndrome · 2025Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAs no study has evaluated the association between fat intake and its components with diabetic foot ulcer (DFU) indices, our aim in the present cross-sectional study was to assess this association.
methodsA total of 300 participants with DFUs were enrolled in this cross-sectional study, which took place at the Diabetes Clinic of Tehran University of Medical Sciences. To assess dietary intake, three 24-h dietary recalls were conducted. In addition to dietary assessments, sociodemographic information, anthropometric measurements and physical activity levels factors were evaluated. The evaluation of foot ulcer indices, including the length, width, and depth, was performed by reviewing the patients' medical records. A physician assessed all the foot ulcer indices.
resultsIntakes of total fat, saturated fatty acid (SFA), monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) increased progressively from the lowest to highest tertile of fat intake (all p < 0.001). No significant associations were observed between foot ulcer dimensions (length, width, depth) and dietary fat intake, including plant/animal oils, cholesterol, omega-3/6, trans fats, or PUFA/SFA ratios (Ptrend > 0.05). However, the (PUFAs + MUFAs)/SFAs ratio showed a significant inverse association with ulcer length in the fully adjusted model (OR: 0.71 vs. 0.42; Ptrend = 0.04).
conclusionIn conclusion, we observed significant associations between an increase in the (PUFAs + MUFAs) / (SFAs) ratio and a notable reduction in foot ulcer length after adjusting for confounders. Further research with larger sample sizes could yield more comprehensive insights.
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