SynthesisParasites & vectors2025
Mosquito vector competence for Japanese encephalitis virus: a systematic review and meta-analysis update.
Synthesis in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Detection of Japanese encephalitis virus inParasite epidemiology and control · 2026Article
- Japanese Encephalitis Virus and Host Innate Immunity: Insights Into TLR Signaling, PRR Crosstalk, and Viral Immune Evasion.Cell biochemistry and function · 2026Review
- Host-specific ubiquitination of prM orchestrates ESCRT recruitment to mediate efficient Japanese Encephalitis Virus assembly in vertebrates.PLoS pathogens · 2026Article
- Investigating habitat preferences and host-feeding behavior of mosquito disease vectors on commercial swine farms in the USA.Parasites & vectors · 2026Article
- Evaluating AI-based mosquito monitoring technologies: a field study in Zhejiang Province, 2025.Frontiers in veterinary science · 2026Article
- Association among persistent chemical pollutants and infectious encephalitis: a mixture exposure and mediation approach.BMC public health · 2025Article
- CC-90009, a Cereblon E3 Ligase Modulator, Exhibits Antiviral Efficacy Against JEV In Vitro and In Vivo via Targeted Degradation of GSPT1 and Viral NS5 Protein.Pharmaceutics · 2025Article
- First characterization of mosquito vector abundance and diversity on commercial swine farms in the United States.Scientific reports · 2025Article
- Managing Japanese Encephalitis Virus as a Veterinary Infectious Disease Through Animal Surveillance and One Health Control Strategies.Life (Basel, Switzerland) · 2025Review
- Characterizing Epidemiological Trends and Associated Factors of Japanese Encephalitis in China: Insights From a 17-Year National Surveillance Analysis.Transboundary and emerging diseases · 2025Article
- Review of selected mosquito-borne diseases: arboviruses (dengue, chikungunya, Zika, West Nile, Japanese encephalitis, yellow fever) and parasitic diseases (malaria, lymphatic Filariasis).Frontiers in public health · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundJapanese encephalitis is an emerging zoonotic disease caused by the Japanese encephalitis virus (JEV), transmitted primarily by mosquitoes of the Culex species. Amid the recent geographical expansion of JEV into Mainland Australia and the dramatic increase in research output, here we provide an update to our 2018 systematic review and meta-analysis, by appraising the scientific literature published from 2016 through 2023 and quantitatively summarizing the data from this update and the 2018 systematic review meta-analysis on vector competence for JEV.
methodsA systematic review of the literature on JEV vector and host competence, published from 2016 through 2023, was performed. Bibliographic databases, PubMed, Scopus, Web of Science, and the Armed Forces Pest Management Board website were searched for relevant literature. Records were screened for relevance for vector competence, specifically: infection rate, dissemination rate, and transmission rate. To estimate the overall and subgroup effect sizes for each mosquito species, random-effects meta-analysis models were utilized. Meta-regression models were fit to evaluate the association between a priori variables-such as mosquito subfamily/tribe, routes of JEV administration for mosquito infection, incubation length, incubation temperatures, and diagnostic methods for JEV detection-and the outcomes of interest.
resultsThis study update includes 74 new reports, identifying 9-12 additional mosquito species as competent for JEV, depending on the specific outcome assessed. The overall JEV infection, dissemination, and transmission rates across all species and studies were 45.4% (95% confidence interval (CI) 35.9-55.2%), 41.2% (95% CI 29.7-53.7%), and 22.7% (95% CI 14.6-33.4%), respectively. Among the subfamilies/tribes, Culicini had the highest infection (51.9%; 95% CI 39.2-64.4%) and transmission (27.8%; 95% CI 16.5-43.1%) rates. Meta-regressions showed mosquito subfamily/tribe was consistently associated with all the outcomes of interest, although the heterogeneity (I
conclusionsThe information presented in this study provides a quantitative summary update on vector competence for JEV. Vector competence data are necessary for risk assessment models, the development of mosquito and virus surveillance programs, and effective prevention and control strategies in regions currently affected by JEV and those at risk of incursion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.