Evidence map›Paper›PMID 40421839›Full record

ArticleTurkish journal of anaesthesiology and reanimation2025

The Potential Renoprotective Effect of Sugammadex in Renal Ischemia-reperfusion Injury.

Vildan Kölükçü, Mehtap Gürler Balta, Ahmet Tuğrul Şahin, Ali Genç, Velid Unsal, Fatih Fırat, Fikret Gevrek, Asiye Yancı, Ahmet Burak Gürpınar

Abstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vildan KölükçüTokat Gaziosmanpaşa University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Tokat, TürkiyeORCID 0000-0002-3914-3899
Mehtap Gürler BaltaTokat Gaziosmanpaşa University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Tokat, TürkiyeORCID 0000-0003-2360-7203
Ahmet Tuğrul ŞahinTokat Gaziosmanpaşa University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Tokat, TürkiyeORCID 0000-0002-4855-696X
Ali GençTokat Gaziosmanpaşa University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Tokat, TürkiyeORCID 0000-0003-1392-0204
Velid UnsalMardin Artuklu University,  Faculty of Health Sciences, and Central Research Laboratory, Mardin, TürkiyeORCID 0000-0003-1415-0563
Fatih FıratTokat Gaziosmanpaşa University Faculty of Medicine, Department of Urology, Tokat, TürkiyeORCID 0000-0003-4283-1374
Fikret GevrekTokat Gaziosmanpaşa University Faculty of Medicine, Department of Histology and Embryology, Tokat, TürkiyeORCID 0000-0002-3722-2542
Asiye YancıTokat Gaziosmanpaşa University Faculty of Medicine, Department of Histology and Embryology, Tokat, TürkiyeORCID 0000-0003-0010-6748
Ahmet Burak GürpınarTokat Gaziosmanpaşa University Faculty of Medicine, Department of Biochemistry, Tokat, TürkiyeORCID 0000-0003-3227-4682

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to evaluate the effectiveness of sugammadex on renal tissue for against ischemia-reperfusion injury. Methods: Twenty-one Wistar albino strain female rats were divided into three groups. The first group functioned as the control cohort for comparison. In Groups 2 and 3, a renal ischemia-reperfusion model was established. Moreover, following the cessation of ischemia, the rats in Group 3 were intravenously administered sugammadex at a dose of 4 mg kg Results: Biochemical analyses revealed a notable increase in the enzymatic activities of glutathione peroxidase and superoxide dismutase in Group 3 relative to Group 2 ( Conclusion: Sugammadex plays a protective role against ischaemia-reperfusion injury in renal tissue.

Indexed as

Ischaemia-reperfusion injuryratrenalsugammadex

Identifiers

PMID40421839
PMCPMC12728449

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.