Evidence map›Paper›PMID 40422031›Full record

ReviewBiosensors2025

Comprehensive Analysis of Advancement in Optical Biosensing Techniques for Early Detection of Cancerous Cells.

Ayushman Ramola, Amit Kumar Shakya, Arik Bergman

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. SPR biosensor with a graphene overlayer for carcinoma detection.Frontiers in bioengineering and biotechnology · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ayushman RamolaDepartment of Electrical and Electronics Engineering, Ariel University, Ariel 40700, Israel.ORCID 0000-0002-1903-5401
Amit Kumar ShakyaDepartment of Electrical and Electronics Engineering, Ariel University, Ariel 40700, Israel.ORCID 0000-0002-7710-4276
Arik BergmanDepartment of Electrical and Electronics Engineering, Ariel University, Ariel 40700, Israel.ORCID 0000-0001-7257-4976

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This investigation presents an overview of various optical biosensors utilized for the detection of cancer cells. It covers a comprehensive range of technologies, including surface plasmon resonance (SPR) sensors, which exploit changes in refractive index (RI) at the sensor surface to detect biomolecular interactions. Localized surface plasmon resonance (LSPR) sensors offer high sensitivity and versatility in detecting cancer biomarkers. Colorimetric sensors, based on color changes induced via specific biochemical reactions, provide a cost-effective and simple approach to cancer detection. Sensors based on fluorescence work using the light emitted from fluorescent molecules detect cancer-specific targets with specificity and high sensitivity. Photonics and waveguide sensors utilize optical waveguides to detect changes in light propagation, offering real-time and label-free detection of cancer biomarkers. Raman spectroscopy-based sensors utilize surface-enhanced Raman scattering (SERS) to provide molecular fingerprint information for cancer diagnosis. Lastly, fiber optic sensors offer flexibility and miniaturization, making them suitable for in vivo and point-of-care applications in cancer detection. This study provides insights into the principles, applications, and advancements of these optical biosensors in cancer diagnostics, highlighting their potential in improving early detection and patient outcomes.

Indexed as

Biosensing TechniquesEarly Detection of CancerNeoplasmsBiomarkers, TumorHumansSpectrum Analysis, RamanSurface Plasmon ResonanceBiomarkers, Tumorcolorimetric sensorsfiber optic sensorsfluorescence-based sensorsLSPR sensorsphotonics and waveguide sensorsSERSSPR sensors

Identifiers

PMID40422031
PMCPMC12109962

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.