Evidence map›Paper›PMID 40422178›Full record

ArticleAntimicrobial agents and chemotherapy2025

The PfK13 G533S mutation confers artemisinin partial resistance in multiple genetic backgrounds of

Faiza Amber Siddiqui, Aongruk Chim-Ong, Chenqi Wang, Jun Miao, Liwang Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Faiza Amber SiddiquiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Aongruk Chim-OngDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Chenqi WangCenter for Global Health and Infectious Diseases Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, Florida, USA.
Jun MiaoDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0001-9374-6749
Liwang CuiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-8338-1974

Funding

Unraveling the Drivers of Persistent Malaria Transmission in Cameroon: A Systems Approach (REDIAL)U19AI181593 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI Rose Leke · 2024 to 2026
$3.0M
NIAID NIH HHS U19 AI181593NIH HHS U19AI181593
6 · The paper itself

Abstract

Mutations in the

Indexed as

AntimalarialsArtemisininsDrug ResistancePlasmodium falciparumProtozoan ProteinsCRISPR-Cas SystemsHumansMalaria, FalciparumMutationAntimalarialsartemisininArtemisininsProtozoan Proteinsartemisinin resistancegene editingPfK13Plasmodium falciparumring-stage survival

Identifiers

PMID40422178
PMCPMC12217484

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.