Evidence map›Paper›PMID 40422679›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

An Assessment of the Antifungal Efficacy of a Novel Topical Onychomycosis Treatment Using Human Nail and Skin Infection Models.

Anthony Brown, Felipe Goñi-de-Cerio, Ainhoa Bilbao, Adrià Ribes, Antonio R Fernández de Henestrosa, Ludmila Prudkin, Paola Perugini, Mónica Foyaca

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Multifunctional Activity ofPlants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anthony BrownInnovation and Development, ISDIN, 08019 Barcelona, Spain.ORCID 0000-0002-1271-310X
Felipe Goñi-de-CerioGAIKER Technology Centre, Basque Research and Technology Alliance (BRTA), 48170 Zamudio, Spain.ORCID 0000-0002-2029-6369
Ainhoa BilbaoGAIKER Technology Centre, Basque Research and Technology Alliance (BRTA), 48170 Zamudio, Spain.ORCID 0000-0002-3139-2903
Adrià RibesInnovation and Development, ISDIN, 08019 Barcelona, Spain.ORCID 0000-0002-5127-2183
Antonio R Fernández de HenestrosaInnovation and Development, ISDIN, 08019 Barcelona, Spain.ORCID 0000-0001-6115-0000
Ludmila PrudkinInnovation and Development, ISDIN, 08019 Barcelona, Spain.ORCID 0000-0001-5747-0706
Paola PeruginiDepartment of Pharmaceutical Chemistry, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-8774-8534
Mónica FoyacaInnovation and Development, ISDIN, 08019 Barcelona, Spain.

Funding

Isdin (Spain) NA
6 · The paper itself

Abstract

Onychomycosis, a fungal nail infection, affects about 4% of the global population. Current topical antifungals like ciclopirox and amorolfine have limited effectiveness, highlighting the need for better treatments. WSNS-PO is a novel water-soluble therapy designed to treat and prevent onychomycosis by enhancing nail health. This study evaluated WSNS-PO's ability to penetrate the nail plate and to treat and prevent infection by

Indexed as

antifungalAspergillus versicolorCandida albicansEpidermophyton floccosumex vivo modelFusarium solaninailonychomycosistopicalTrichophyton rubrum

Identifiers

PMID40422679
PMCPMC12112648

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.