Evidence map›Paper›PMID 40422802›Full record

ArticleMarine drugs2025

Dihydrogeodin from

Abdul Wahab Akram, Dae-Cheol Choi, Hyung-Kyu Chae, Sung Dae Kim, Dongmi Kwak, Bong-Sik Yun, Man Hee Rhee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Biomedicines · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdul Wahab AkramDepartment of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-0244-1945
Dae-Cheol ChoiDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan 54596, Republic of Korea.ORCID 0009-0003-7664-5454
Hyung-Kyu ChaeDepartment of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-6876-9460
Sung Dae KimDepartment of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Dongmi KwakDepartment of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-0876-3179
Bong-Sik YunDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan 54596, Republic of Korea.
Man Hee RheeDepartment of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-3088-1318

Funding

National Research Foundation of Korea (NRF) 2022R1A2C1012963
6 · The paper itself

Abstract

Cardiovascular disease remains a leading cause of morbidity and mortality worldwide, frequently arising from platelet hyperactivation and subsequent thrombus formation. Although conventional antiplatelet therapies are available, challenges, such as drug resistance and bleeding complications, require the development of novel agents. In this study, dihydrogeodin (DHG) was isolated from

Indexed as

Calcium SignalingPlatelet AggregationPlatelet Aggregation InhibitorsAnimalsBlood PlateletsDown-RegulationHumansMaleMAP Kinase Signaling SystemMitogen-Activated Protein KinasesPhosphatidylinositol 3-KinasesPlatelet Glycoprotein GPIIb-IIIa ComplexProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleySignal TransductionMitogen-Activated Protein KinasesPhosphatidylinositol 3-KinasesPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexProto-Oncogene Proteins c-aktdihydrogeodinFennellia flavipesMAPK and PI3K/Akt pathwaysmarine natural productsplatelet aggregation

Identifiers

PMID40422802
PMCPMC12112792

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.