Evidence mapPaperPMID 40422832Full record

ReviewJournal of functional biomaterials2025

Emerging Trends in Microfluidic Biomaterials: From Functional Design to Applications.

Jiaqi Lin, Lijuan Cui, Xiaokun Shi, Shuping Wu

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiaqi LinInstitute of Polymer Materials, School of Materials Science & Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0009-0000-3749-1577
Lijuan CuiInstitute of Polymer Materials, School of Materials Science & Engineering, Jiangsu University, Zhenjiang 212013, China.
Xiaokun ShiInstitute of Polymer Materials, School of Materials Science & Engineering, Jiangsu University, Zhenjiang 212013, China.
Shuping WuInstitute of Polymer Materials, School of Materials Science & Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0001-7289-3109

Funding

National Natural Science Foundation of China 51808263
6 · The paper itself

Abstract

The rapid development of microfluidics has driven innovations in material engineering, particularly through its ability to precisely manipulate fluids and cells at microscopic scales. Microfluidic biomaterials, a cutting-edge interdisciplinary field integrating microfluidic technology with biomaterials science, are revolutionizing biomedical research. This review focuses on the functional design and fabrication of organ-on-a-chip (OoAC) platforms via 3D bioprinting, explores the applications of biomaterials in drug delivery, cell culture, and tissue engineering, and evaluates the potential of microfluidic systems in advancing personalized healthcare. We systematically analyze the evolution of microfluidic materials-from silicon and glass to polymers and paper-and highlight the advantages of 3D bioprinting over traditional fabrication methods. Currently, despite significant advances in microfluidics in medicine, challenges in scalability, stability, and clinical translation remain. The future of microfluidic biomaterials will depend on combining 3D bioprinting with dynamic functional design, developing hybrid strategies that combine traditional molds with bio-printed structures, and using artificial intelligence to monitor drug delivery or tissue response in real time. We believe that interdisciplinary collaborations between materials science, micromachining, and clinical medicine will accelerate the translation of organ-on-a-chip platforms into personalized therapies and high-throughput drug screening tools.

Indexed as

3D bioprintingmedical applicationsmicrofluidic biomaterialsmicrofluidic technologyorgan-on-a-chip

Identifiers

PMID40422832
PMCPMC12112458

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.