ArticleNanomaterials (Basel, Switzerland)2025
Microstructural and Elemental Characterization of Calcium Silicate-Based Sealers.
Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy of novel biomaterials versus traditional materials in the treatment of dental and pulpal diseases: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Evaluation of the physicochemical properties and adhesive interface quality of BioRoot Flow and BioRoot RCS endodontic sealers: An in vitro study.Clinical oral investigations · 2026Article
- In Vitro Comparison of Void Formation Between Calcium Silicate-Based Sealers and AH Plus: A Systematic Review and Meta-Analysis.Dentistry journal · 2026Review
- Influence of intracanal moisture on dentinal tubule infiltration of a calcium silicate-containing resin-based sealer assessed with confocal laser scanning microscopy.BMC oral health · 2026Article
- Fabrication and characterization of a bioactive glass and tricalcium silicate incorporated resin-based root canal sealer.Journal of conservative dentistry and endodontics · 2026Article
- Physical properties comparison of four bioceramic vs. epoxy resin-based root canal sealers: an in vitro study.BMC oral health · 2026Article
- Dentinal tubule penetration of AH Plus, MTA Fillapex, and BioRoot flow: a confocal laser scanning microscopy study.BMC oral health · 2025Article
- New Glass-Ceramics in the System CaMaterials (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium silicate-based sealers (CSBS) vary in chemical composition, which can influence treatment outcomes. Therefore, the study aimed at comparing several commercially available CSBS regarding microstructure and elemental characterization. Four CSBS (AH Plus Bioceramic Sealer, BioRoot RCS, BioRoot Flow, TotalFill BC Sealer) and a control resin-based sealer (AH Plus) were evaluated using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray powder diffraction analysis (XRD). The specimens were analyzed after setting (SEM, EDX, XRD), as well as after 7 (SEM) and 28 days (SEM, EDX) of incubation in Hank's balanced salt solution. AH Plus exhibited a uniform matrix and small amounts of calcium (Ca), significantly decreasing after incubation. In contrast, CSBSs exhibited crystalline forms on the surface and increased Ca content, significantly increasing after 28 days of incubation. The main crystalline phase for all tested CSBS was zirconium oxide, while for ERBS it was calcium tungstate. In conclusion, the amount of calcium increased on the surface of CSBSs after incubation, which alkalinized the pH, promoting mineralization, apatite formation, and antibacterial potential. Despite this, the formation of a hydroxyapatite layer was not demonstrated, possibly due to the high dissolution potential of CSBSs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.