Evidence map›Paper›PMID 40423231›Full record

ReviewNeurology international2025

The Role of Tau in Neuronal Function and Neurodegeneration.

Gonzalo Emiliano Aranda-Abreu, Fausto Rojas-Durán, María Elena Hernández-Aguilar, Deissy Herrera-Covarrubias, Luis Isauro García-Hernández, María Rebeca Toledo-Cárdenas, Donají Chi-Castañeda

Abstract readReview
In one paragraph

Review in Neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Promoter mutagenesis and a massively parallel reporter screen of thebioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gonzalo Emiliano Aranda-AbreuInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0001-8519-5473
Fausto Rojas-DuránInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0003-4497-0909
María Elena Hernández-AguilarInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0002-1617-5636
Deissy Herrera-CovarrubiasInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0001-5752-4700
Luis Isauro García-HernándezInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0001-6967-1919
María Rebeca Toledo-CárdenasInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0003-1273-4944
Donají Chi-CastañedaInstituto de Investigaciones Cerebrales, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, Col. Industrial Animas, Xalapa 91190, Mexico.ORCID 0000-0002-2094-5787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tau protein plays a pivotal role in maintaining neuronal structure and function through its regulation of microtubule stability and neuronal polarity. Encoded by the

Indexed as

Alzheimer’s diseaseglial cellsmicrotubulesneurodegenerationtauopathiesTau protein

Identifiers

PMID40423231
PMCPMC12114167

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.