Association of Hospitalizations With Randomized Glycemia-Lowering Treatment in GRADE.

What the trial testedrandomised · 9,877 people · 2025

Randomised comparison

−22%−34% to −8%

Bigger than 5 in 10 for adverse events & safety

As reported

HR 0.78, 95% CI 0.66–0.92

the abstract, start to end

… in the AT data set (hazard ratio 0.78 [95% CI 0.66, 0.92]; P = …

← favours treatmentfavours comparator →

could be chance

Adverse events & safety

HR 0.780.66–0.92

GLP-1 receptor agonistsSulfonylureas & glinidesAdverse events & safety

GLP-1 receptor agonists × adverse events & safetyharms?mixed

unlikelylikely

0.020.02 without it

Sulfonylureas & glinides × adverse events & safetyharms?mixed

unlikelylikely

0.000.25 without it

← favours treatmentfavours comparator →

this papermore certainless certain

1 / 5