Evidence map›Paper›PMID 40424206›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2025

The bronchoalveolar proteome changes in obesity.

William G Tharp, Carlos A Gartner, Yulica Santos-Ortega, Calvin P Vary, S Patrick Bender, Anne E Dixon

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Pulmonary iron oxide (FeHuman & experimental toxicology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William G TharpDepartment of Anesthesiology, University of Vermont, Burlington, Vermont, United States.ORCID 0000-0003-4642-8750
Carlos A GartnerCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, Maine, United States.ORCID 0009-0009-5986-611X
Yulica Santos-OrtegaCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, Maine, United States.
Calvin P VaryCenter for Molecular Medicine, MaineHealth Institute for Research, Scarborough, Maine, United States.
S Patrick BenderDepartment of Anesthesiology, University of Vermont, Burlington, Vermont, United States.
Anne E DixonDepartment of Medicine, University of Vermont, Burlington, Vermont, United States.

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI Susan L SANTANGELO · 2017 to 2026
$51.6M
The role of night shift work in metabolic disorders during and after pregnancyP20GM121301 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$25.1M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) L30HL149005-01HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM121301HHS | NIH | National Institute of General Medical Sciences (NIGMS) U54GM115516International Anesthesia Research Society (IARS)NHLBI NIH HHS L30 HL149005NIGMS NIH HHS P20 GM121301NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

Obesity contributes to pulmonary dysfunction through poorly understood biochemical mechanisms. Chronic inflammation and altered cellular metabolism have emerged as pathological changes across organ systems in obesity, but whether similar changes occur in lungs with obesity is unknown. We collected bronchoalveolar lavage fluid (BALF) from right upper lobe and lingula pulmonary subsegments of 14 adults (7 males/7 females) with body mass indexes (BMIs) ranging from 24.3 to 50.9 kg/m

Indexed as

Bronchoalveolar Lavage FluidLungObesityProteomeAdultBody Mass IndexFemaleHumansMaleMiddle AgedProteomicsProteomebronchoalveolar lavagelungobesityproteome

Identifiers

PMID40424206
PMCPMC12258624

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.