Evidence map›Paper›PMID 40424241›Full record

ArticlePloS one2025

Genome-wide scan for signatures of selection in Hanwoo and Angus cattle using whole-genome sequence data.

Hyoun Ju Kim, Nasir Moghaddar, Sam Clark, Julius H J van der Werf, Sara de Las Heras-Saldana

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyoun Ju KimSchool of Environmental and Rural Science, University of New England, Armidale, New South Wales, Australia.ORCID https://orcid.org/0000-0002-7785-6339
Nasir MoghaddarSchool of Environmental and Rural Science, University of New England, Armidale, New South Wales, Australia.
Sam ClarkSchool of Environmental and Rural Science, University of New England, Armidale, New South Wales, Australia.
Julius H J van der WerfSchool of Environmental and Rural Science, University of New England, Armidale, New South Wales, Australia.
Sara de Las Heras-SaldanaAGBU, a Joint Venture of NSW Department of Primary Industries and Regional Development and University of New England, Armidale, New South Wales, Australia.ORCID https://orcid.org/0000-0002-8665-6160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study used whole-genome sequence data on 406 beef cattle (203 Hanwoo and 203 Angus) to detect signatures of selection using four different methods; integrated haplotype score (iHS), Rsb, XP-EHH, and runs of homozygosity (ROH). Based on Rsb and XP-EHH analysis, 36 and 21 genomic regions differed significantly between Angus and Hanwoo breeds. Within breeds, we identified 108 regions (76 in Hanwoo and 32 in Angus) with the ROH analysis and 331 regions with the iHS method (298 in Hanwoo and 33 in Angus). The candidate genes related to meat quality, such as HSPA9 and LPL, were found within Hanwoo, while genes associated with growth and meat quantity traits, including ACTC1 and TMEM68, were identified within Angus. This study can assist in understanding the selection history of these breeds and identifying the genomic regions associated with the traits selected for in the breeding programs for these cattle breeds.

Indexed as

GenomeSelection, GeneticWhole Genome SequencingAnimalsBreedingCattleGenome-Wide Association StudyHaplotypesHomozygotePolymorphism, Single Nucleotide

Identifiers

PMID40424241
PMCPMC12111605

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.