Evidence map›Paper›PMID 40424999›Full record

ReviewThe American journal of tropical medicine and hygiene2025

Intravenous Levosimendan for Acute Heart Failure with Renal Impairment Following Severe Scorpion Envenomation: Case Report and Literature Review.

Karama Bouchaala, Mabrouk Bahloul, Amina Hadded, Oussama Haddar, Chokri Ben Hamida

Abstract readCase ReportsReview
In one paragraph

Review in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karama BouchaalaDepartment of Intensive Care, Habib Bourguiba University Hospital, Sfax University, Sfax, Tunisia.
Mabrouk BahloulDepartment of Intensive Care, Habib Bourguiba University Hospital, Sfax University, Sfax, Tunisia.
Amina HaddedDepartment of Intensive Care, Habib Bourguiba University Hospital, Sfax University, Sfax, Tunisia.
Oussama HaddarDepartment of Cardiology, Hedi Chaker University Hospital, Sfax University, Sfax, Tunisia.
Chokri Ben HamidaDepartment of Intensive Care, Habib Bourguiba University Hospital, Sfax University, Sfax, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute heart failure, presenting as either cardiogenic shock or pulmonary edema, is the main cause of mortality because of scorpion envenomation (SE) in many tropical and subtropical parts of the world. Standard heart failure treatment, including inotropes and diuretics to treat cardiogenic shock and pulmonary edema, was used in most studies. However, the role of the inotrope levosimendan in the treatment of cardiogenic shock complicated by pulmonary edema and renal impairment after SE has rarely been reported, to the best of our knowledge. Here, we report this case of severe SE complicated by cardiogenic shock and pulmonary edema successfully managed with levosimendan in a 4-year-old patient. As a consequence, the use of this inotropic drug seems to be beneficial in severe cases of SE complicated by severe cardiogenic shock and not stabilized by the usually used inotropic and vasopressor agents (dobutamine and noradrenaline). Further studies are needed to confirm the usefulness of levosimendan in cardiogenic shock related to severe SE.

Indexed as

Cardiotonic AgentsHeart FailureHydrazonesPyridazinesRenal InsufficiencyScorpion StingsShock, CardiogenicAnimalsChild, PreschoolHumansMalePulmonary EdemaScorpionsSimendanCardiotonic AgentsHydrazonesPyridazinesSimendan

Identifiers

PMID40424999
PMCPMC12360093

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.