Evidence map›Paper›PMID 40425083›Full record

ArticleJournal of advanced research2026

Burden of female diseases among adolescents and young adults aged 10-24 years in South Asia and Sub-Saharan Africa, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021.

Jiahong Sun, Yongliang Zhu, Danyi Huang, Liuqing Li, Mengna Pan, Fei Li, Chuanwei Ma

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Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

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7 authors.

Jiahong SunDepartment of Preventive Medicine, School of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808 Guangdong, China.
Yongliang ZhuDepartment of Epidemiology and Health Statistics, School of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523808, China.
Danyi HuangDepartment of Epidemiology and Health Statistics, School of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523808, China.
Liuqing LiDepartment of Preventive Medicine, School of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808 Guangdong, China.
Mengna PanDepartment of Epidemiology and Health Statistics, School of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523808, China.
Fei LiDepartment of Childcare and Wellness, the First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523710, China.
Chuanwei MaDepartment of Epidemiology and Health Statistics, School of Public Health, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523808, China. Electronic address: chuanweima@gdmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFemale diseases pose significant challenges in South Asia and Sub-Saharan Africa, particularly among adolescent girls and young women, who often receive insufficient attention.

objectivesTo report patterns and trends of female diseases among adolescent girls and young females aged 10-24 years in South Asia and Sub-Saharan Africa from 1990 to 2021.

methodsWe used data from the Global Burden of Disease Study 2021 for 51 countries in South Asia and Sub-Saharan Africa between 1990 and 2021. Joinpoint Regression was used to calculate annual average percentage changes and 95 % confidence intervals to quantify temporal trends.

resultsIn 2021, South Asia and Sub-Saharan Africa had high mortality rates of maternal disorders of 6.04 (95 % uncertainty intervals 5.02, 7.39) and 17.69 (14.37, 21.78) per 100,000 population, respectively. The mortality rates for female cancers were approximately 0.98 in both regions, and the incidence rates for gynecological diseases were 16472.83 and 14480.99, per 100,000 population, respectively. From 1990 to 2021, there was an increasing trend in the number of maternal disorder deaths in Sub-Saharan Africa, as well as in all metric rates for most female cancers in both regions, and disability-adjusted life years, prevalence, and incidence rates for gynecological diseases in South Asia. Several female diseases varied across countries and were increasingly affecting younger adolescents aged 10-14 years in both regions. Although countries with lower Socio-demographic Index had a heavier burden of female diseases, no significant association was observed between the Universal Health Coverage effective coverage index and death rates for female cancers or gynecological diseases.

conclusionsThe burden of female diseases remains high among young females in South Asia and Sub-Saharan Africa, with younger adolescents being particularly affected. This underscores the urgent need for targeted interventions and increased investment in healthcare infrastructure to reduce the burden of female diseases in these regions.

Indexed as

Genital Diseases, FemaleGlobal Burden of DiseaseAdolescentAfrica South of the SaharaAsiaAsia, SouthernChildCost of IllnessFemaleHumansIncidenceYoung AdultAdolescentsFemale diseaseGlobal Burden of Disease StudySouth AsiaSub-Saharan AfricaYoung adults

Identifiers

PMID40425083
PMCPMC12957813

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.