Evidence map›Paper›PMID 40425646›Full record

ArticleScientific reports2025

Nutrient intakes and metabolomic profiles associated with animal source energy percentage in children's diets.

Topi Hovinen, Elina Kettunen, Maijaliisa Erkkola, Anu Suomalainen, Riitta Freese, Liisa Korkalo

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Topi Hovinen *Research Programs Unit, Stem Cells and Metabolism, University of Helsinki, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0001-9853-6572
Elina Kettunen *Department of Food and Nutrition, University of Helsinki, 00014, Helsinki, Finland.ORCID http://orcid.org/0000-0002-4328-9495
Maijaliisa ErkkolaDepartment of Food and Nutrition, University of Helsinki, 00014, Helsinki, Finland.ORCID http://orcid.org/0000-0002-6966-1523
Anu SuomalainenResearch Programs Unit, Stem Cells and Metabolism, University of Helsinki, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0003-4833-5195
Riitta FreeseDepartment of Food and Nutrition, University of Helsinki, 00014, Helsinki, Finland.ORCID http://orcid.org/0000-0002-6833-2736
Liisa KorkaloDepartment of Food and Nutrition, University of Helsinki, 00014, Helsinki, Finland. liisa.korkalo@helsinki.fi.ORCID http://orcid.org/0000-0002-0525-9877

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the study was to calculate the relative intake of animal source energy (animal source energy percentage, ASEP) and examine its utility in nutrition and metabolic research with a special attention on children. In addition, the capacity of ASEP to identify potential metabolic biomarkers of plant-forward diets was tested. Four-day food records and 7-day dietary screeners of 51 Finnish children aged 1-7 years, consuming a vegan (n = 7), pesco-/lacto-/ovo-vegetarian (n = 11) or omnivorous diet (n = 33), were used for assessing general performance of ASEP as diet measure. Blood samples of 40 children (six vegans, eight vegetarians, 26 omnivores) were analyzed for plasma LDL cholesterol, erythrocyte folate concentration and serum untargeted MS-metabolomics. Estimated ASEPs varied between 0% and 52%. Vegetarians and omnivores showed overlapping ASEPs. ASEP had a strong positive correlation with saturated fatty acid (percent of energy, E%; r = 0.785) and cholesterol intake (r = 0.715) and a strong negative correlation with fibre (r = - 0.811) and polyunsaturated fatty acid (E%; r = - 0.819) intake. ASEP also correlated with plasma LDL cholesterol (r = 0.699) concentration. Serum indoleacrylic acid (IAA) is suggested to be further investigated as a possible biomarker of plant-forward diet. ASEP provides a useful tool for objective and quantitative assessment of diet characteristics in research.

Indexed as

DietEnergy IntakeMetabolomeMetabolomicsNutrientsAnimalsBiomarkersChildChild, PreschoolDiet, VegetarianFemaleFinlandFolic AcidHumansInfantMaleBiomarkersFolic AcidNutrientsASEPCholesterolDiet classificationIndoleacrylic acidPlant-based dietary patternVegan diet

Identifiers

PMID40425646
PMCPMC12116860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.