ArticleBMC plant biology2025
Integrative multi-omics analysis reveals the potential mechanism by which Streptomyces pactum Act12 enhances wheat root drought tolerance by coordinating phytohormones and metabolic pathways.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Integrative Transcriptomic and Metabolomic Analyses Provide Insights into the Regulatory Basis ofPlants (Basel, Switzerland) · 2026Article
- Manipulating root-associated microbiomes to boost drought resistance in dryland winter wheat with Streptomyces pactum Act12.BMC microbiology · 2026Article
- Untargeted Metabolomics Reveals Raw Material Geographic Origin as a Key Factor Shaping the Quality of Ginger-Derived Exosome-like Nanovesicles.Foods (Basel, Switzerland) · 2026Article
- Rhizosphere microbiome engineering with PGPR to combat soil-mediated climate change.Frontiers in microbiology · 2026Review
- Unveiling Genetic Loci for Root Morphology and Salt Response at Rice Seedling Stage via Genome-Wide Association Studies.Life (Basel, Switzerland) · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundDrought stress is one of the major abiotic stresses that limit wheat growth and yield. Streptomyces, a class of plant growth-promoting rhizobacteria (PGPR) with multifarious metabolic potential and remarkable stress resistance properties in soil, have significant potential in enhancing the drought tolerance of crops. However, the molecular mechanisms by which Streptomyces improve the drought tolerance function of the wheat root are poorly understood.
resultsIn this study, we investigated the role and molecular mechanisms of Streptomyces pactum Act12 in regulating the drought tolerance of wheat root by combining pot experiments and multi-omics techniques. The pot experiment results demonstrated that under drought stress, Act12 treatment significantly promoted the development of the wheat root system, including the total root length, surface area, number of root tips, and diameter. Furthermore, Act12 treatment increased the activity of antioxidant enzymes (SOD activity increased by 23.7%), the content of osmotic regulators proline (265.8%) and soluble protein (116.8%), and significantly decreased the content of malondialdehyde (39.0%). The integrated analysis of the transcriptome and metabolome demonstrated that Act12 might promote root development through the synergistic regulation of phytohormone signaling. Concurrently, it might optimize energy supply and enhance the stability of cell membranes via the regulation of metabolic pathways, including glycolysis, the tricarboxylic acid (TCA) cycle, and glycerophospholipid metabolism.
conclusionConsequently, Act12 enhanced the drought adaptability of the wheat root system from multiple perspectives. This study reveals the central role of Act12 in the regulation of drought resistance in plants and provides a theoretical basis for the development of drought-resistant biologics based on Streptomyces.
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