Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors.
Isa SerranoCIISA-Center for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade Técnica, 1300-477 Lisbon, Portugal.ORCID 0000-0002-3115-1392
Dalila Mil-HomensiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-9727-3579
Rita F PiresiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0003-3678-1462
Vasco D B BonifácioiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0003-2349-8473
Joana F GuerreiroCIISA-Center for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade Técnica, 1300-477 Lisbon, Portugal.ORCID 0000-0003-1960-603X
Eva CunhaCIISA-Center for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade Técnica, 1300-477 Lisbon, Portugal.ORCID 0000-0002-5641-4400
Sofia S CostaGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), R. da Junqueira 100, 1349-008 Lisbon, Portugal.ORCID 0000-0002-4096-2410
Luís TavaresCIISA-Center for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade Técnica, 1300-477 Lisbon, Portugal.
Manuela OliveiraCIISA-Center for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade Técnica, 1300-477 Lisbon, Portugal.ORCID 0000-0002-3910-1525
Funding
FCT/Associate Laboratory Institute for Health and Bioeconomy (i4HB) LA/P/0140/2020FCT/Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL) LA/P/0117/2020FCT/CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal UIDB/00276/2020FCT/Global Health and Tropical Medicine (GHTM) UID/04413/2020FCT/Laboratório Associado para Ciência Animal e Veterinária LA/P/0059/2020 - AL4AnimalSFCT/Research Unit Institute for Bioengineering and Biosciences (iBB) UIDB/04565/2020; UIDP/04565/2020Fundação para a Ciência e a Tecnologia (FCT) PTDC/SAUINF/28466/2017; PTDC/MEC-ONC/29327/2017
6 · The paper itself
Abstract
BACKGROUND/
objectivesDiabetic foot infections (DFIs) are commonly associated with frequent hospitalizations, limb amputations, and premature death due to the profile of the bacteria infecting foot ulcers. DFIs are generally colonized by a polymicrobial net of bacteria that grows in biofilms, developing an increased antimicrobial resistance to multiple antibiotics. DFI treatment is a hurdle, and the need to develop new therapies that do not promote resistance is urgent. Therefore, the antibacterial efficacy of Nisin Z (antimicrobial peptide), a core-shell polycationic polyurea pharmadendrimer (PURE
methodsThe antibacterial activity was analyzed in vitro by determining the minimal inhibitory concentration (MIC) and in vivo in a
resultsThe results indicate that Nisin Z exhibited antibacterial activity against
conclusionsThese findings suggest that both Nisin Z and PURE
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
In Vivo Antimicrobial Activity of Nisin Z Against · full record | Socratic