Evidence map›Paper›PMID 40426840›Full record

ArticleBiomedicines2025

Disparate Molecular Properties of Two Hypertrophic Cardiomyopathy-Associated cMyBP-C Mutants Reveal Distinct Pathogenic Mechanisms Beyond Haploinsufficiency.

Angelos Thanassoulas, Emna Riguene, Maria Theodoridou, Laila Barrak, Hamad Almaraghi, Mohammed Hussain, Sahar Isa Da'as, Mohamed A Elrayess, F Anthony Lai, Michail Nomikos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Angelos ThanassoulasCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-4390-4854
Emna RigueneCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Maria TheodoridouBiomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Laila BarrakCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0009-0000-5095-146X
Hamad AlmaraghiCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Mohammed HussainCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Sahar Isa Da'asResearch Department, Sidra Medicine, Doha P.O. Box 26999, Qatar.ORCID 0000-0003-3438-5028
Mohamed A ElrayessCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3803-4604
F Anthony LaiCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-2852-8547
Michail NomikosCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.

Funding

Qatar University QUCG-CMED-22/23-514
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiac diseasecMyBP-CHCMhypertrophic cardiomyopathyMyBPC3

Identifiers

PMID40426840
PMCPMC12109454

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.