Evidence mapPaperPMID 40427405Full record

ReviewAntioxidants (Basel, Switzerland)2025

Takotsubo Syndrome and Oxidative Stress: Physiopathological Linkage and Future Perspectives.

Alfredo Mauriello, Carmen Del Giudice, Gerardo Elia Del Vecchio, Adriana Correra, Anna Chiara Maratea, Martina Grieco, Arianna Amata, Vincenzo Quagliariello, Nicola Maurea, Riccardo Proietti and 3 more

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alfredo MaurielloS.C. Cardiologia, Istituto Nazionale Tumori, IRCCS, Fondazione "G. Pascale", 80131 Naples, Italy.ORCID 0000-0001-7060-6938
Carmen Del GiudiceCardiology Unit, Boscotrecase Hospital, ASL NA3Sud, 81042 Boscotrecase, Italy.
Gerardo Elia Del VecchioCardiology Unit, "A. Guerriero" Hospital, ASL CE, 81025 Marcianise, Italy.
Adriana CorreraIntensive Cardiac Care Unit, "San Giuseppe Moscati" Hospital, ASL CE, 81031 Aversa, Italy.
Anna Chiara MarateaS.C. Cardiologia, Istituto Nazionale Tumori, IRCCS, Fondazione "G. Pascale", 80131 Naples, Italy.
Martina GriecoCardiology Unit, S. Giovanni Bosco Hospital, ASL NA1, 80100 Naples, Italy.
Arianna AmataDepartment of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Vincenzo QuagliarielloS.C. Cardiologia, Istituto Nazionale Tumori, IRCCS, Fondazione "G. Pascale", 80131 Naples, Italy.
Nicola MaureaS.C. Cardiologia, Istituto Nazionale Tumori, IRCCS, Fondazione "G. Pascale", 80131 Naples, Italy.ORCID 0000-0003-3704-0092
Riccardo ProiettiLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool L8 7TX, UK.
Antonio GiordanoSbarro Institute for Cancer Research and Molecular Medicine and Center of Biotechnology, College of Science and Technology, Temple University, BioLife Science Bldg, Suite 431-1900 N 12th Street, Philadelphia, PA 19122, USA.
Antonello D'AndreaCardiology and Intensive Care Unit, Department of Cardiology, "Umberto I" Hospital, 84014 Nocera Inferiore, Italy.ORCID 0000-0002-9698-9145
Vincenzo RussoCardiology Unit, Department of Medical and Translational Sciences, University of Campania "Luigi Vanvitelli", Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0002-9227-0360

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo syndrome (TTS) is an acute coronary syndrome of unknown prevalence with a physiopathological mechanism that is not yet fully understood. The course is generally benign. Current therapeutic management is based on limited evidence. Oxidative stress seems to play a role in the pathogenesis of cardiovascular diseases, especially regarding the endothelial dysfunction underlying TTS. The present review aims to describe the pathophysiological mechanisms linking oxidative stress and TTS, explore the impact of oxidative stress on TTS, and evaluate the efficacy of anti-oxidative stress therapies on TTS.

Indexed as

acute coronary syndromecancerheart failureoxidative stressTakotsubo syndrome

Identifiers

PMID40427405
PMCPMC12108290

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.